UAS regulatory sequences drive expression of a short inverted repeat.
Somatic clones expressing kisHMS01254 under the control of Scer\GAL4Tub.PU contain a greater overall number of cells and significantly more intestinal stem cells in adult flies compared to controls.
Expressing kisHMS01254 under the control of Scer\GAL4esg.PU together with Scer\GAL80Su(H).GBE (in combination with a Gal80[ts] transgene to restrict expression to the adult stage) results in significantly more intestinal stem cells in adult flies compared to controls.
Expression of kisHMS01254 under the control of Scer\GAL4bbg-C96 results in a fraction of individuals exhibiting wing nicking.
Scer\GAL4Tub.PU, kisHMS01254 has increased cell number | somatic clone | adult stage phenotype, suppressible | partially by CblS.UAS, Scer\GAL4Tub.PU
Scer\GAL4Tub.PU, kisHMS01254 has increased cell number | somatic clone | adult stage phenotype, suppressible by CblL.UAS, Scer\GAL4Tub.PU
Scer\GAL4bbg-C96/kisHMS01254 is a suppressor of visible phenotype of Scer\GAL4bbg-C96, domRNAi.Sym.UAS
Scer\GAL4Tub.PU, kisHMS01254 has adult midgut epithelium | somatic clone phenotype, suppressible | partially by CblS.UAS, Scer\GAL4Tub.PU
Scer\GAL4Tub.PU, kisHMS01254 has adult midgut epithelium | somatic clone phenotype, suppressible by CblL.UAS, Scer\GAL4Tub.PU
Scer\GAL4Tub.PU, kisHMS01254 has intestinal stem cell | somatic clone | adult stage phenotype, suppressible | partially by CblS.UAS, Scer\GAL4Tub.PU
Scer\GAL4Tub.PU, kisHMS01254 has intestinal stem cell | somatic clone | adult stage phenotype, suppressible by CblL.UAS, Scer\GAL4Tub.PU
Scer\GAL4bbg-C96/kisHMS01254 is a suppressor of wing phenotype of Scer\GAL4bbg-C96, domRNAi.Sym.UAS
Co-expression of kisHMS01254 suppresses the wing nicking phenotype of flies expressing domdsRNA.Sym.Scer\UAS under the control of Scer\GAL4bbg-C96.