FlyBase Allele Report: Dmel\egr[UAS.cUa]

General Information

Symbol

Dmel\egr^UAS.cUa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Unknown

FlyBase ID

FBal0276788

Feature type

allele

Associated gene

Dmel\egr

Associated Insertion(s)

Carried in Construct

P{UAS-egr.U}

Also Known As

UAS-egr, UAS-Eiger

Key Links

Transgenic product class

wild_type

(Jones et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Jones et al., 2012)

Mutagen

in vitro construct

(Jones et al., 2012)

Progenitor genotype

Carried in construct

P{UAS-egr.U}

Cytology

Description

UAS regulatory sequences drive expression of egr.

(Jones et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

egr

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of carcinoma

CEA with N^ICN.UAS

(Pallavi et al., 2012)

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates cancer

modeled by Hipk^UAS.Tag:HA

(Blaquiere et al., 2018)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/larval plasmatocyte, with Scer\GAL4^Hml.PG

(Jones et al., 2012)

eye, with Scer\GAL4^GMR.PF

(Jones et al., 2012, Jones et al., 2008)

wing disc, with Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

wing disc | third instar larval stage, with Scer\GAL4^dpp.PU

(Brodsky et al., 2004)

wing disc | third instar larval stage, with Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

Detailed Description

Statement

Reference

Expressing egr^UAS.cUa under the control of Scer\GAL4^dpp.blk1 primarily causes an invasive phenotype in the wing disc but has little effect on the overall wing disc size.

(Blaquiere et al., 2018)

Expression of egr^UAS.cUa under the control of Scer\GAL4^rn-GAL4-5 (with tub-Gal80[ts] restricting expression to third instar larvae) leads to apoptosis and cellular debris in wing disc around wing pouch (wing pouches are regenerated 72 hours after expression has ceased) in larvae while it leads to relatively normal sized wing blades, no ectopic wings and normal appearing thorax in adults compared to controls.

(Worley et al., 2018)

Constitutive expression of egr^Scer\UAS.cUa in the retina under the control of Scer\GAL4^GMR.PF results in an extreme small eye phenotype.

Expression of egr^Scer\UAS.cUa under the control of Scer\GAL4^Hml.PG results in a reduction in the number of plasmatocytes compared with controls.

Flies expressing egr^Scer\UAS.cUa in plasmatocytes under the control of Scer\GAL4^Hml.PG show significantly reduced survival rate following parental infection with Micrococcus luteus only between 5 and 8 days post infection, compared with control flies.

(Jones et al., 2012)

Expression of egr^Scer\UAS.cUa under the control of Scer\GAL4^GMR.PF results in a strong small eye phenotype.

(Jones et al., 2008)

Expression of egr^Scer\UAS.cUa under the control of Scer\GAL4^dpp.PU induces apoptosis at the anterior-posterior boundary of the third instar larval wing disc.

(Brodsky et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, enhanceable by upd1^UAS.cUa, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

BacA\p35^UAS.cHa, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, enhanceable by CtBP[+]/CtBP^87De-10

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, enhanceable by BacA\p35^UAS.cHa, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, enhanceable by upd1^UAS.cUa, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

Ilp8^UAS.cUa, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, enhanceable by CtBP[+]/CtBP^334Δ4

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, mirr¹⁴⁸⁶ has visible | adult stage phenotype, enhanceable by CtBP[+]/CtBP^334Δ4

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, mirr¹⁸²⁵ has visible | adult stage phenotype, enhanceable by CtBP[+]/CtBP^334Δ4

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, upd1^UAS.cUa has visible | adult stage phenotype, enhanceable by CtBP[+]/CtBP^87De-10

(Worley et al., 2018)

CtBP^UAS.Tag:FLAG, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, enhanceable by CtBP[+]/CtBP^87De-10

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, enhanceable by Ilp8^UAS.cUa, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, enhanceable by mirr¹⁴⁸⁶/mirr[+]

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, enhanceable by mirr¹⁸²⁵/mirr[+]

(Worley et al., 2018)

NOT Enhanced by

Statement

Reference

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, non-enhanceable by Df(3L)XR38

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, non-enhanceable by Dronc^C318S.UAS, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, upd1^UAS.cUa has visible | adult stage phenotype, non-enhanceable by upd2^Δ/upd2[+]/upd3^Δ/upd3[+]

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, non-enhanceable by upd1[+]/upd1^YM55

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, non-enhanceable by wg^{UAS.cHa.Tag:HA}, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, non-enhanceable by Ilp8[+]/Ilp8^MI00727

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has increased cell death | third instar larval stage phenotype, non-enhanceable by CtBP[+]/CtBP^87De-10

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, non-enhanceable by CtBP^UAS.Tag:FLAG, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

Suppressed by

Statement

Reference

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, suppressible | partially by hep[+]/hep^r75

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, suppressible by bsk^K53R.UAS, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, suppressible by kay^Fbz.UAS, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, suppressible by upd2[+]/upd2^Δ

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, suppressible by upd3^Δ/upd2[+]/upd3[+]/upd2^Δ

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, suppressible | partially by upd3^Δ/upd3[+]

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, suppressible | partially by wg¹/wg[+]

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, suppressible by Ilp8^MI00727/Ilp8^MI00727

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has increased cell death | third instar larval stage phenotype, suppressible | partially by Scer\GAL4^rn-GAL4-5/kay^Fbz.UAS

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, suppressible | partially by CtBP^Tag:FLAG

(Worley et al., 2018)

Scer\GAL4^GMR.PF, egr^UAS.cUa has visible phenotype, suppressible | partially by Asam\aopP^UAS.Tag:MYC, Scer\GAL4^GMR.PF

(Jones et al., 2012)

Scer\GAL4^GMR.PF, egr^UAS.cUa has visible phenotype, suppressible by Styp\AvrA^UAS.cJa/Scer\GAL4^GMR.PF

(Jones et al., 2012)

Scer\GAL4^GMR.PF, egr^UAS.cUa has visible phenotype, suppressible by Styp\AvrA^UAS.Tag:MYC/Scer\GAL4^GMR.PF

(Jones et al., 2008)

Scer\GAL4^GMR.PF, egr^UAS.cUa has abnormal size phenotype, suppressible by Styp\AvrA^UAS.Tag:MYC/Scer\GAL4^GMR.PF

(Jones et al., 2008)

NOT suppressed by

Statement

Reference

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, non-suppressible by Df(3L)XR38

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, non-suppressible by Dronc^C318S.UAS, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, upd1^UAS.cUa has visible | adult stage phenotype, non-suppressible by upd2^Δ/upd2[+]/upd3^Δ/upd3[+]

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, non-suppressible by upd1[+]/upd1^YM55

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, non-suppressible by Ilp8[+]/Ilp8^MI00727

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has increased cell death | third instar larval stage phenotype, non-suppressible by CtBP[+]/CtBP^87De-10

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype, non-suppressible by CtBP^UAS.Tag:FLAG, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

Scer\GAL4^GMR.PF, egr^UAS.cUa has visible phenotype, non-suppressible by Asam\aopP^{C177A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF

(Jones et al., 2012)

Scer\GAL4^GMR.PF, egr^UAS.cUa has visible phenotype, non-suppressible by Styp\AvrA^m.UAS/Scer\GAL4^GMR.PF

(Jones et al., 2012)

Scer\GAL4^GMR.PF, egr^UAS.cUa has visible phenotype, non-suppressible by Styp\AvrA^{m.UAS.Tag:MYC}/Scer\GAL4^GMR.PF

(Jones et al., 2008)

Scer\GAL4^GMR.PF, egr^UAS.cUa has abnormal size phenotype, non-suppressible by Styp\AvrA^{m.UAS.Tag:MYC}/Scer\GAL4^GMR.PF

(Jones et al., 2008)

NOT Enhancer of

Statement

Reference

egr^UAS.cUa, Scer\GAL4^dpp.blk1 is a non-enhancer of abnormal cell migration | larval stage phenotype of Hipk^UAS.Tag:HA, Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

Suppressor of

Statement

Reference

egr^UAS.cUa, Scer\GAL4^dpp.blk1 is a suppressor | partially of abnormal cell migration | larval stage phenotype of Hipk^UAS.Tag:HA, Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

NOT Suppressor of

Statement

Reference

egr^UAS.cUa, Scer\GAL4^dpp.blk1 is a non-suppressor | partially of abnormal cell migration | larval stage phenotype of Hipk^UAS.Tag:HA, Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

Other

Statement

Reference

CtBP⁰³⁴⁶³, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^GMR76A01, Scer\GAL4^nub-AC-62, egr^UAS.cUa has visible | adult stage phenotype

(Worley et al., 2018)

BacA\p35^UAS.cHa, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype

(Worley et al., 2018)

Df(3R)Exel8157, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype

(Worley et al., 2018)

Ilp8^UAS.cUa, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, mirr¹⁴⁸⁶ has visible | adult stage phenotype

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, mirr¹⁸²⁵ has visible | adult stage phenotype

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, upd1^UAS.cUa has visible | adult stage phenotype

(Worley et al., 2018)

CtBP^148Δ2, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype

(Worley et al., 2018)

CtBP^N148PY, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype

(Worley et al., 2018)

CtBP^UAS.Tag:FLAG, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has visible | adult stage phenotype

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^GMR15B03, Scer\GAL4^nub-AC-62, egr^UAS.cUa has visible | adult stage phenotype

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^nub-AC-62, egr^UAS.cUa has visible | adult stage phenotype

(Worley et al., 2018)

Phenotype Manifest In

Enhanced by

Statement

Reference

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, enhanceable by upd1^UAS.cUa, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, enhanceable by BacA\p35^UAS.cHa, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, enhanceable by upd1^UAS.cUa, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing pouch | third instar larval stage | ectopic phenotype, enhanceable by upd1^UAS.cUa, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing disc | third instar larval stage phenotype, enhanceable by CtBP[+]/CtBP^87De-10

(Worley et al., 2018)

BacA\p35^UAS.cHa, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, enhanceable by CtBP[+]/CtBP^87De-10

(Worley et al., 2018)

Ilp8^UAS.cUa, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, enhanceable by CtBP[+]/CtBP^334Δ4

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, mirr¹⁴⁸⁶ has wing | ectopic phenotype, enhanceable by CtBP[+]/CtBP^334Δ4

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, mirr¹⁸²⁵ has wing | ectopic phenotype, enhanceable by CtBP[+]/CtBP^334Δ4

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, upd1^UAS.cUa has wing | ectopic phenotype, enhanceable by CtBP[+]/CtBP^87De-10

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, enhanceable by Ilp8^UAS.cUa, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^UAS.Tag:FLAG, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, enhanceable by CtBP[+]/CtBP^87De-10

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, enhanceable by mirr¹⁴⁸⁶/mirr[+]

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, enhanceable by mirr¹⁸²⁵/mirr[+]

(Worley et al., 2018)

NOT Enhanced by

Statement

Reference

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, non-enhanceable by Df(3L)XR38

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, non-enhanceable by Dronc^C318S.UAS, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, upd1^UAS.cUa has wing | ectopic phenotype, non-enhanceable by upd2^Δ/upd2[+]/upd3^Δ/upd3[+]

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, non-enhanceable by upd1[+]/upd1^YM55

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, non-enhanceable by wg^{UAS.cHa.Tag:HA}, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, non-enhanceable by Ilp8[+]/Ilp8^MI00727

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, non-enhanceable by CtBP^UAS.Tag:FLAG, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

Suppressed by

Statement

Reference

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, suppressible by bsk^K53R.UAS, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, suppressible by kay^Fbz.UAS, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, suppressible | partially by hep[+]/hep^r75

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, suppressible by upd2[+]/upd2^Δ

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, suppressible by upd3^Δ/upd2[+]/upd3[+]/upd2^Δ

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, suppressible | partially by upd3^Δ/upd3[+]

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, suppressible | partially by wg¹/wg[+]

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, suppressible by Ilp8^MI00727/Ilp8^MI00727

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing disc | third instar larval stage phenotype, suppressible | partially by Scer\GAL4^rn-GAL4-5/kay^Fbz.UAS

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, suppressible | partially by CtBP^Tag:FLAG

(Worley et al., 2018)

Scer\GAL4^GMR.PF, egr^UAS.cUa has eye phenotype, suppressible | partially by Asam\aopP^UAS.Tag:MYC, Scer\GAL4^GMR.PF

(Jones et al., 2012)

Scer\GAL4^GMR.PF, egr^UAS.cUa has eye phenotype, suppressible by Styp\AvrA^UAS.cJa/Scer\GAL4^GMR.PF

(Jones et al., 2012)

Scer\GAL4^GMR.PF, egr^UAS.cUa has eye phenotype, suppressible by Styp\AvrA^UAS.Tag:MYC/Scer\GAL4^GMR.PF

(Jones et al., 2008)

NOT suppressed by

Statement

Reference

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, upd1^UAS.cUa has wing | ectopic phenotype, non-suppressible by upd2^Δ/upd2[+]/upd3^Δ/upd3[+]

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, non-suppressible by upd1[+]/upd1^YM55

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, non-suppressible by Ilp8[+]/Ilp8^MI00727

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, non-suppressible by CtBP^UAS.Tag:FLAG, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, non-suppressible by Df(3L)XR38

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype, non-suppressible by Dronc^C318S.UAS, Scer\GAL4^rn-GAL4-5

(Worley et al., 2018)

Scer\GAL4^GMR.PF, egr^UAS.cUa has eye phenotype, non-suppressible by Asam\aopP^{C177A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF

(Jones et al., 2012)

Scer\GAL4^GMR.PF, egr^UAS.cUa has eye phenotype, non-suppressible by Styp\AvrA^m.UAS/Scer\GAL4^GMR.PF

(Jones et al., 2012)

Scer\GAL4^GMR.PF, egr^UAS.cUa has eye phenotype, non-suppressible by Styp\AvrA^{m.UAS.Tag:MYC}/Scer\GAL4^GMR.PF

(Jones et al., 2008)

Enhancer of

Statement

Reference

egr^UAS.cUa, Scer\GAL4^dpp.blk1 is an enhancer of wing disc phenotype of Hipk^UAS.Tag:HA, Scer\GAL4^dpp.blk1

(Blaquiere et al., 2018)

Other

Statement

Reference

CtBP⁰³⁴⁶³, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype

(Worley et al., 2018)

BacA\p35^UAS.cHa, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype

(Worley et al., 2018)

Df(3R)Exel8157, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype

(Worley et al., 2018)

Ilp8^UAS.cUa, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, mirr¹⁴⁸⁶ has wing | ectopic phenotype

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, mirr¹⁸²⁵ has wing | ectopic phenotype

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype

(Worley et al., 2018)

Scer\GAL4^rn-GAL4-5, egr^UAS.cUa, upd1^UAS.cUa has wing | ectopic phenotype

(Worley et al., 2018)

CtBP^148Δ2, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype

(Worley et al., 2018)

CtBP^334Δ4, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype

(Worley et al., 2018)

CtBP^N148PY, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype

(Worley et al., 2018)

CtBP^UAS.Tag:FLAG, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing | ectopic phenotype

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^rn-GAL4-5, egr^UAS.cUa has wing pouch | ectopic | third instar larval stage phenotype

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^GMR15B03, Scer\GAL4^nub-AC-62, egr^UAS.cUa has wing | ectopic phenotype

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^nub-AC-62, egr^UAS.cUa has wing | ectopic phenotype

(Worley et al., 2018)

CtBP^87De-10, Scer\GAL4^GMR76A01, Scer\GAL4^nub-AC-62, egr^UAS.cUa has wing | ectopic phenotype

(Worley et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of egr^UAS.cUa under the control of Scer\GAL4^rn-GAL4-5 (with tub-Gal80[ts] restricting expression to third instar larvae) in Df(3R)Exel8157/+, CtBP⁰³⁴⁶³/+, CtBP^334Δ4/+, CtBP^N148PY, CtBP^148Δ2, mirr¹⁴⁸⁶/+ or mirr¹⁸²⁵/+ background; or in combination with expression of Ilp8^UAS.cUa, CtBP^UAS.Tag:FLAG (occasionally), upd1^UAS.cUa or BacA\p35^UAS.cHa leads to ectopic wings compared to controls.

Expression of egr^UAS.cUa under the control of Scer\GAL4^rn-GAL4-5 (with tub-Gal80[ts] restricting expression to third instar larvae) in combination with wg^{UAS.cHa.Tag:HA}, Dronc^C318S.UAS, CtBP^Tag:FLAG, CtBP^HMS00677, kay^Fbz.UAS, bsk^K53R.UAS or CtBP^JF01291; or in the background of wg¹/+, hep^r75/+, Df(3L)XR38/+, upd2^Δ/+, upd3^Δ/+, upd1^YM55/+ or upd2^Δ/+ upd3^Δ/+ does not lead to ectopic wings compared to controls.

Expression of egr^UAS.cUa under the control of Scer\GAL4^nub-AC-62 (but not Scer\GAL4^GMR15B03, Scer\GAL4^GMR76A01, or Scer\GAL4^dpp.blk1) alone or together with either Scer\GAL4^GMR15B03 or Scer\GAL4^GMR76A01 (with tub-Gal80[ts] restricting expression to third instar larvae) in CtBP^87De-10/+ background (but not in wild type background) leads to ectopic wings compared to controls.

In CtBP^87De-10/+ background expression of egr^UAS.cUa under the control of Scer\GAL4^rn-GAL4-5 (with tub-Gal80[ts] restricting expression to third instar larvae) leads to either no ectopic wings (in majority) or ectopic wings (24-hour-expression yielding a lower frequency than 40-hour-expression) on one or two sides compared to controls. Ectopic wings occur most frequently when expression is induced on early stages of third instar larvae. After expression has ceased, wing discs exhibit morphological changes associated with the outgrowth of an ectopic wing pouch from the posterior edge of the notum.

(Worley et al., 2018)

Xenogenetic Interactions

Statement

Reference

Co-expression of egr^UAS.cUa and BacA\p35^UAS.cHa under the control of Scer\GAL4^rn-GAL4-5 (with tub-Gal80[ts] restricting expression to third instar larvae) leads to ectopic wings compared to controls.

(Worley et al., 2018)

Co-expression of Zzzz\aopP^{Scer\UAS.T:Hsap\MYC} with egr^Scer\UAS.cUa under the control of Scer\GAL4^GMR.PF partially rescues the eye phenotype resulting from the overexpression of egr^Scer\UAS.cUa. While the size of the Zzzz\aopP^{Scer\UAS.T:Hsap\MYC}-rescued eye is marginally larger than the eyes expressing egr^Scer\UAS.cUa alone, black necrotic tissue is clearly visible within the eye tissue.

Co-expression of Styp\AvrA^Scer\UAS.cJa with egr^Scer\UAS.cUa under the control of Scer\GAL4^GMR.PF compeltely rescues the eye phenotype resulting from the overexpression of egr^Scer\UAS.cUa.

(Jones et al., 2012)

Expression of Styp\AvrA^{Scer\UAS.T:Hsap\MYC} completely suppresses the small eye phenotype seen when egr^Scer\UAS.cUa is expressed under the control of Scer\GAL4^GMR.PF.

Expression of Styp\AvrA^{m.Scer\UAS.T:Hsap\MYC} does not suppress the small eye phenotype seen when egr^Scer\UAS.cUa is expressed under the control of Scer\GAL4^GMR.PF.

(Jones et al., 2008)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

egr^Scer\UAS.cUa

egr^UAS.cUa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Unknown

Secondary FlyBase IDs

References (11)

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