FB2024_03 , released June 25, 2024
Allele: Dmel\par-1UAS.Tag:MYC.cHa
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General Information
Symbol
Dmel\par-1UAS.Tag:MYC.cHa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct of Huang
FlyBase ID
FBal0302932
Feature type
allele
Associated gene
Dmel\par-1
Associated Insertion(s)
Carried in Construct
P{UAS-Myc-par-1.H}
Key Links
Transgenic product class
wild_type
(Huang et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Huang et al., 2013)
Mutagen
in vitro construct
(Huang et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-Myc-par-1.H}
Cytology
Description

UAS regulatory sequences drive expression of par-1 tagged at the N-terminal end with Tag:MYC.

(Huang et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
par-1
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of two copies of par-1Scer\UAS.T:Hsap\MYC.cHa under the control of Scer\GAL4GMR.PU results in rough eyes without a discernible overgrowth.

      Expression of par-1Scer\UAS.T:Hsap\MYC.cHa under the control of Scer\GAL4Bx-MS1096 results in enlarged wings and a wing bending-down phenotype. When par-1Scer\UAS.T:Hsap\MYC.cHa is expressed under the control of Scer\GAL4hh-Gal4 the relative P-compartment area of the wing is increased compared to controls.

      (Huang et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Enhancer of
      Statement
      Reference

      par-1UAS.Tag:MYC.cHa/Scer\GAL4GMR.PU is an enhancer of visible phenotype of Scer\GAL4GMR.PU, ykiUAS.cZa

      (Huang et al., 2013)
      Phenotype Manifest In
      Suppressed by
      Enhancer of
      Statement
      Reference

      par-1UAS.Tag:MYC.cHa/Scer\GAL4GMR.PU is an enhancer of eye phenotype of Scer\GAL4GMR.PU, ykiUAS.cZa

      (Huang et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of par-1Scer\UAS.T:Hsap\MYC.cHa enhances the eye overgrowth phenotype seen when ykiScer\UAS.cZa is expressed under the control of Scer\GAL4GMR.PU.

      Co-expression of sddsRNA.N.Scer\UAS and sddsRNA.C.Scer\UAS suppresses the overgrowth phenotype seen in wings expressing par-1Scer\UAS.T:Hsap\MYC.cHa under the control of Scer\GAL4Bx-MS1096.

      (Huang et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      par-1Scer\UAS.T:Hsap\MYC.cHa
      par-1UAS.Tag:MYC.cHa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct of Huang
      Secondary FlyBase IDs
        References (1)