Hearts of Scer\GAL4tin.CΔ4>p53DN.Scer\UAS.cUa adult flies appear to have normal structure and function.
Scer\GAL4Act5C.PU/p53DN.UAS.cUa is a suppressor of increased cell death | embryonic stage phenotype of Scer\GAL4Act5C.PU, dppUAS.cUa
p53DN.UAS.cUa/Scer\GAL4how-24B is a suppressor of increased cell death | embryonic stage phenotype of Scer\GAL4how-24B, Tak1UAS.cTa
p53DN.UAS.cUa/Scer\GAL4how-24B is a suppressor of increased cell death | embryonic stage phenotype of raw1
p53DN.UAS.cUa/Scer\GAL4tin.CΔ4 is a suppressor of adult heart phenotype of Scer\GAL4tin.CΔ4, ScoxGD898
p53DN.UAS.cUa/Scer\GAL4tin.CΔ4 is a suppressor of cardiac myofibril | adult stage phenotype of Scer\GAL4tin.CΔ4, ScoxGD898
p53DN.UAS.cUa/Scer\GAL4tin.CΔ4 is a suppressor of adult heart muscle cell phenotype of Scer\GAL4tin.CΔ4, ScoxGD898
p53DN.UAS.cUa/Scer\GAL4how-24B is a suppressor of embryonic cardioblast phenotype of raw1
p53DN.UAS.cUa/Scer\GAL4how-24B is a suppressor of embryonic pericardial cell phenotype of raw1
Co-expression of p53DN.Scer\UAS.cUa suppresses heart function and structure defects seen in Scer\GAL4tin.CΔ4>ScoxGD898 flies: diastolic interval, heart period and fractional shortening return to control levels and there are no obvious morphological heart defects (including correct alignment of cardiomyocyte myofibrils).