RpS5, M(1)o, M(1)15D
Please see the JBrowse view of Dmel\RpS5a for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.52
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.55
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\RpS5a using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\RpS5a in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Haploinsufficient locus.
RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short, monopolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.
Minute gene.
Molecularly-defined mutations in RpS5a result in Minute phenotypes.
RpS5a lies in a gap in deletion coverage.
Mutant alleles have the developmental delay and bristle phenotype that makes them useful as markers in clonal analysis.
A clone (λDmS18) containing a ribosomal protein gene that may encode an RPS18 protein has been identified. The clone hybridises in situ to 15B and may correspond to RpS5a.
Burns et al. (FBrf0041468) identified a clone that hybrid-selected an RNA that translated to give a protein identified as RPS18. The clone (λDmS18) hybridized in situ to 15B and these authors concluded that "M(1)o" (i.e. RpS5a) encoded this protein. McKim and Hawley ( EMBL:U48394 ) have shown, however, that RpS5a encodes RPS5; the status of the gene encoded by λDmS18 remains uncertain.
One of a class of genes (see MIN record) that when present in one, rather than two, copies, produce a characteristic phenotype consisting of short slender bristles and delayed development. Eclosion delayed 35 hr (Ferrus, 1975).
