Cul-2, l(2)02074
Please see the JBrowse view of Dmel\Cul2 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cul2 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
Cul2 protein is found in germline cells at all stages of development. It is enriched in pernuclear regions of the germline cells. In mid-oogenesis, the perinuclear cytoplasm is transported to the posterior end forming the pole plasm, where Cul2 continues to be expressed. Cul2 protein was also found to be present in somatic cells at all developmental stages from germarium to developing egg chambers.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Cul2 in JBrowse2-54
2-54.6
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
S2 cells are treated with dsRNA made from templates generated with primers directed against this gene to assess effect on degradation of dup and geminin genes.
Source for merge of: cul-2 l(2)02074
"l(2)02074" probably corresponds to "CG1512"; the P{PZ} insertion in the "l(2)0207402074" allele maps only 24bp upstream of the 5' end of the CT3821 transcript of "CG1512".
Source for identity of: Cul2 cul-2
Renamed to be consistent with FlyBase nomenclature rules.
