Amino acid replacement: S5R. Amino acid replacement: L21W. Amino acid replacement: A887T. Figure 1 and the text concerning this allele are at odds - the text is correct (note from N. Baker).
C21523103A
C14A
S5R | Egfr-PA
S5R
One of two nucleotide substitutions affecting the amino acid sequence in the EgfrE1 mutant relative to the reference sequence.
G21557607A
G3165A
A887T | Egfr-PA; A936T | Egfr-PB
A887T
One of two nucleotide substitutions affecting the amino acid sequence in the EgfrE1 mutant relative to the reference sequence. A L21W change is also reported in FBrf0105872 but a W already exists at this location in the reference sequence.
Heterozygous eyes are small and rough.
The number of ommatidial clusters is significantly reduced in EgfrE1/+ larval eye discs, resulting in a small rough eye phenotype.
Mutant flies have an extra wing vein phenotype with an additional vein fragment above vein L2 and some vein deltas.
EgfrE1 heterozygous flies display abnormal wing vein morphology. This phenotype is compromised by treatment with the Hsp90 inhibitor 17-AAG.
Heterozygotes have extra wing vein material in the wing.
Heterozygotes have a rough eye phenotype.
In EgfrE1/+ adults, the number of ommatidia with pale-type R8 cells and yellow-type R7 cells is significantly increased. Many of these are found in pale-yellow hybrid ommatidia with a yellow-type R7 and a pale-type R8.
EgfrE1 mutants exhibit ectopic wing veins.
Heterozygotes have a rough eye phenotype, with elliptical eyes and disarranged ommatidial arrays, and wing vein L2 shows an abnormal broadening at the wing margin.
EgfrE1 heterozygotes exhibit a slight rough eye phenotype.
EgfrE1 mutants exhibit ectopic wing vein formation.
EgfrE1 homozygous adults are small and have greatly reduced numbers of ommatidia with large gaps of pigmented tissue between them. Heterozygous adults have normal eyes.
Heterozygous adults have smaller eyes than normal which have moderate rough phenotype.
EgfrE1/+ flies have rough eyes and a weak extra wing vein phenotype.
Wings of heterozygous and homozygous flies have extra wing vein material.
Heterozygotes have smaller eyes than normal which are mispatterned.
EgfrE1/+ flies have a rough eye phenotype.
Heterozygous mutants do not cause any defects in the ocellar sensory system (OSS) neurogenesis or axon guidance.
Heterozygotes have smaller eyes than normal and lack some ommatidia, producing an irregular arrangement of facets.
Heterozygotes have rough eyes. This phenotype is suppressed towards wild-type in transheterozygous combination with Egfrf24. This phenotype is suppressed towards wild-type in transheterozygous combination with Egfrtsla at 28oC but not at 18oC. Heterozygotes show greatly reduced ommatidial cluster formation in the morphogenetic furrow of the eye disc.
Heterozygotes exhibit roughening of patches on both eyes. Homozygotes exhibit strong blistering, including loss of pigmentation, in patches on both eyes. Rhabdomere assembly is disordered with extra material at the apical ends of the ommatidia. Ommatidia pattern is disordered.
Heterozygotes have rough eyes.
Heterozygotes have a mild rough eye phenotype due to a disrupted ommatidial array.
Displays locomotor activity rhythm with an approximately 24h period.
Extra wing veins close to the wing margin.
Mutation has no effect on rhohs.sev rough eye phenotype.
Rough eye phenotype: eyes are small and rough at the perimeter, ommatidia and hairs are in an irregular pattern.
Homozygous eye discs have fewer ommatidia than wild-type. Outgrowth of photoreceptor axons is disturbed, occurring in many directions. Cell death is abundant in the region approximately corresponding to columns 10-15 in wild-type. In the adult eye the ommatidia are separated by numerous pigment cells and mechanosensory bristles. Wing veins show thickening and plexus formation. Enhances the wing phenotype of Df(1)N-54l9, N264-39, Dl9P, and DlKX6 mutations, and the eye phenotype of Nspl-1.
Mild roughening of the eye.
Homozygotes have fewer ommatidia than wild-type.
The array of ommatidia is less regular in heterozygotes than in wild-type flies, and there is a slight disturbance in the wing vein pattern. Homozygotes have much smaller eyes than normal, containing many fewer ommatidia, and some regions lack ommatidia entirely. These regions contain cells resembling the pigment cells that normally surround each ommatidium, and also mechanosensory bristles. Most ommatidia contain the normal number and arrangement of cells. Only approximately one tenth of the normal number of preclusters differentiate in the eye imaginal discs.
Eyes of EgfrE1/+ heterozygotes rough and more oval than wild type; also display a slight disturbance of the wing-vein pattern. Homozygotes have smaller eyes with many fewer ommatidia and some regions lack them entirely; those ommatidia that are formed contain the normal number and arrangement of cells; the regions without ommatidia contain cells that resemble pigment cells and mechanosensory bristles; only about one tenth the normal number of preommatidial cell clusters differentiate behind the morphogenetic furrow. EgfrE1 in heterozygous combination with a deficiency or null mutation for Egfr is normal in phenotype indicating that EgfrE1 alleles are hypermorphic.
EgfrE1 has visible phenotype, enhanceable by Scer\GAL4Act5C.PU/AdamTS-BKK108644
EgfrE1 has visible | dominant phenotype, enhanceable by Dhc64C6-10
EgfrE1 has visible | dominant phenotype, enhanceable by Dhc64C4-19
EgfrE1 has visible | dominant phenotype, enhanceable by Gl[+]/DCTN1-p150Gl-1
EgfrE1 has visible | dominant phenotype, enhanceable by Mi-2S047526/Mi-2[+]
EgfrE1 has visible | dominant phenotype, enhanceable by Pp1-87B[+]/Pp1-87Bj6E7
EgfrE1 has visible | dominant phenotype, enhanceable by l(3)06803[+]/l(3)0680306803
EgfrE1 has visible | dominant phenotype, enhanceable by l(3)S001405S001405/l(3)S001405[+]
EgfrE1 has visible | dominant phenotype, enhanceable by l(3)S003704S003704/l(3)S003704[+]
EgfrE1 has visible | dominant phenotype, enhanceable by l(3)S057101[+]/l(3)S057101S057101
EgfrE1 has visible | dominant phenotype, enhanceable by twsS049902/tws[+]
EgfrE1 has visible | dominant phenotype, enhanceable by vn[+]/vnunspecified
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S024329S024329/l(3)S024329[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S024833[+]/l(3)S024833S024833
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S026238S026238/l(3)S026238[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S026421S026421/l(3)S026421[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S046604S046604/l(3)S046604[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S056113[+]/l(3)S056113S056113
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S066607[+]/l(3)S066607S066607
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S068808S068808/l(3)S068808[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S081003S145911/l(3)S081003[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S090114[+]/l(3)S090114S090114
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S092708[+]/l(3)S092708S092708
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S133117[+]/l(3)S133117S133117
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S135703S135703/l(3)S135703[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S142909S142909/l(3)S142909[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)j4B9j4B9/l(3)j4B9[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)j5B6j5B6/l(3)j5B6[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by stgS024503/stg[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by CycAS054513/CycA[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by DeltaS049520/Dl[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by Mi-2S005504/Mi-2[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by Mi-2S147412/Mi-2[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by Sin3A[+]/Sin3A08269
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)06906[+]/l(3)0690606906
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S000710[+]/l(3)S000710S000710
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S000718[+]/l(3)S000718S000718
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S009515[+]/l(3)S009515S009515
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S012805S012805/l(3)S012805[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S016805[+]/l(3)S016805S016805
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S019203S141715/l(3)S019203[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S023549S023549/l(3)S023549[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S023549S090101/l(3)S023549[+]
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S023708[+]/l(3)S023708S023708
EgfrE1 has visible | dominant phenotype, non-enhanceable by l(3)S023901[+]/l(3)S023901S023901
EgfrE1 has abnormal size | dominant phenotype, suppressible by Ptp61F[+]/Ptp61F4-10
EgfrE1 has abnormal size | dominant phenotype, suppressible by Ptp61FRNAi.UAS.WIZ/Scer\GAL4GMR.PU
EgfrE1 has abnormal size | dominant phenotype, suppressible by Ptp61FUAS.cBa/Scer\GAL4GMR.PU
EgfrE1 has visible phenotype, suppressible by mir-998exc222
EgfrE1 has visible phenotype, suppressible by Scer\GAL4Act5C.PU/Sulf1UAS.cBa
EgfrE1 has visible | dominant phenotype, suppressible by Gl[+]/DCTN1-p150Gl-1
EgfrE1 has visible | dominant phenotype, suppressible by bonS048706/bon[+]
EgfrE1 has visible | dominant phenotype, suppressible by l(3)j2D5j2D5/l(3)j2D5[+]
EgfrE1 has visible phenotype, suppressible by klu[+]/kluunspecified
EgfrE1 has visible phenotype, suppressible by Ras85DSutor-341/Ras85D[+]
EgfrE1 has visible phenotype, suppressible by Ras85D[+]/Ras85DSutor-404
EgfrE1 has visible phenotype, suppressible by Sos[+]/SosSutor-157
EgfrE1 has visible phenotype, suppressible by SosSutor-405/Sos[+]
EgfrE1 has visible phenotype, suppressible by Su(tor)1-1[+]/Su(tor)1-1134
EgfrE1 has visible phenotype, suppressible by Su(tor)1-119/Su(tor)1-1[+]
EgfrE1 has visible phenotype, suppressible by Su(tor)2-180[+]/Su(tor)2-1801
EgfrE1 has visible phenotype, suppressible by Su(tor)2-2371/Su(tor)2-237[+]
EgfrE1 has visible phenotype, suppressible by Su(tor)2-278[+]/Su(tor)2-2781
EgfrE1 has visible phenotype, suppressible by Su(tor)2-321[+]/Su(tor)2-3211
EgfrE1 has visible phenotype, suppressible by Su(tor)2-3[+]/Su(tor)2-31
EgfrE1 has visible phenotype, suppressible by Su(tor)2-3[+]/Su(tor)2-3361
EgfrE1 has visible phenotype, suppressible by Su(tor)2-4081/Su(tor)2-408[+]
EgfrE1 has visible phenotype, suppressible by Su(tor)3-1[+]/Su(tor)3-138
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)06906[+]/l(3)0690606906
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S000710[+]/l(3)S000710S000710
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S000718[+]/l(3)S000718S000718
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S009515[+]/l(3)S009515S009515
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S012805S012805/l(3)S012805[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S016805[+]/l(3)S016805S016805
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S019203S141715/l(3)S019203[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S023549S023549/l(3)S023549[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S023549S090101/l(3)S023549[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S023708[+]/l(3)S023708S023708
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S023901[+]/l(3)S023901S023901
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S024329S024329/l(3)S024329[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S024833[+]/l(3)S024833S024833
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S026238S026238/l(3)S026238[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S026421S026421/l(3)S026421[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S046604S046604/l(3)S046604[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S056113[+]/l(3)S056113S056113
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S066607[+]/l(3)S066607S066607
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S068808S068808/l(3)S068808[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S081003S145911/l(3)S081003[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S090114[+]/l(3)S090114S090114
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S092708[+]/l(3)S092708S092708
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S133117[+]/l(3)S133117S133117
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S135703S135703/l(3)S135703[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)S142909S142909/l(3)S142909[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)j4B9j4B9/l(3)j4B9[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by l(3)j5B6j5B6/l(3)j5B6[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by stgS024503/stg[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by CycAS054513/CycA[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by DeltaS049520/Dl[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by Mi-2S005504/Mi-2[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by Mi-2S147412/Mi-2[+]
EgfrE1 has visible | dominant phenotype, non-suppressible by Sin3A[+]/Sin3A08269
Egfr[+]/EgfrE1 is an enhancer of visible phenotype of Pi3K68DKD.UAS.Tag:MYC, Scer\GAL469B
EgfrE1 is an enhancer of visible phenotype of BacA\p35GMR.PH, DpGMR.PD, E2f1GMR.PD
EgfrE1 is a non-enhancer of visible phenotype of upd1GMR.PB
EgfrE1 is a suppressor of visible phenotype of PtpmegUAS.cLa, Scer\GAL4en.PU
EgfrE1 is a suppressor of abnormal size | third instar larval stage phenotype of Df(3L)γ3/vnγ4
EgfrE1 is a suppressor of decreased body size | third instar larval stage phenotype of Df(3L)γ3/vnγ4
EgfrE1 is a non-suppressor of visible phenotype of upd1GMR.PB
Egfr[+]/EgfrE1, Pi3K68DUAS.Tag:MYC, Scer\GAL469B has visible phenotype
EgfrE1 has eye phenotype, enhanceable by Ptp61FUAS.cBa/Scer\GAL4GMR.PU
EgfrE1 has wing vein | ectopic phenotype, enhanceable by Scer\GAL4Act5C.PU/AdamTS-BKK108644
EgfrE1 has eye phenotype, enhanceable by Dhc64C6-10
EgfrE1 has eye phenotype, enhanceable by Dhc64C4-19
EgfrE1 has eye phenotype, enhanceable by Gl[+]/DCTN1-p150Gl-1
EgfrE1 has eye phenotype, enhanceable by Mi-2S047526/Mi-2[+]
EgfrE1 has eye phenotype, enhanceable by Pp1-87B[+]/Pp1-87Bj6E7
EgfrE1 has eye phenotype, enhanceable by l(3)06803[+]/l(3)0680306803
EgfrE1 has eye phenotype, enhanceable by l(3)S001405S001405/l(3)S001405[+]
EgfrE1 has eye phenotype, enhanceable by l(3)S003704S003704/l(3)S003704[+]
EgfrE1 has eye phenotype, enhanceable by l(3)S057101[+]/l(3)S057101S057101
EgfrE1 has eye phenotype, enhanceable by twsS049902/tws[+]
EgfrE1 has ommatidium phenotype, enhanceable by kek1unspecified/kek1unspecified
EgfrE1 has wing vein | ectopic phenotype, enhanceable by kek1unspecified/kek1unspecified
EgfrE1 has eye phenotype, enhanceable by kek1unspecified/kek1unspecified
EgfrE1 has phenotype, enhanceable by lilliXS407
EgfrE1 has phenotype, enhanceable by lilliXS575
EgfrE1 has ommatidium phenotype, enhanceable by astK6/ast[+]
EgfrE1 has eye phenotype, enhanceable by vn[+]/vnunspecified
EgfrE1 has ommatidium phenotype, enhanceable by aop[+]/aop1
EgfrE1 has ommatidium phenotype, enhanceable by aop[+]/aop2
EgfrE1 has ommatidium phenotype, enhanceable by aop[+]/aope2d
EgfrE1 has eye phenotype, enhanceable by Df(2L)ast2
EgfrE1 has eye phenotype, non-enhanceable by l(3)S024329S024329/l(3)S024329[+]
EgfrE1 has eye phenotype, non-enhanceable by l(3)S024833[+]/l(3)S024833S024833
EgfrE1 has eye phenotype, non-enhanceable by l(3)S026238S026238/l(3)S026238[+]
EgfrE1 has eye phenotype, non-enhanceable by l(3)S026421S026421/l(3)S026421[+]
EgfrE1 has eye phenotype, non-enhanceable by l(3)S046604S046604/l(3)S046604[+]
EgfrE1 has eye phenotype, non-enhanceable by l(3)S056113[+]/l(3)S056113S056113
EgfrE1 has eye phenotype, non-enhanceable by l(3)S066607[+]/l(3)S066607S066607
EgfrE1 has eye phenotype, non-enhanceable by l(3)S068808S068808/l(3)S068808[+]
EgfrE1 has eye phenotype, non-enhanceable by l(3)S081003S145911/l(3)S081003[+]
EgfrE1 has eye phenotype, non-enhanceable by l(3)S090114[+]/l(3)S090114S090114
EgfrE1 has eye phenotype, non-enhanceable by l(3)S092708[+]/l(3)S092708S092708
EgfrE1 has eye phenotype, non-enhanceable by l(3)S133117[+]/l(3)S133117S133117
EgfrE1 has eye phenotype, non-enhanceable by l(3)S135703S135703/l(3)S135703[+]
EgfrE1 has eye phenotype, non-enhanceable by l(3)S142909S142909/l(3)S142909[+]
EgfrE1 has eye phenotype, non-enhanceable by l(3)j4B9j4B9/l(3)j4B9[+]
EgfrE1 has eye phenotype, non-enhanceable by l(3)j5B6j5B6/l(3)j5B6[+]
EgfrE1 has eye phenotype, non-enhanceable by stgS024503/stg[+]
EgfrE1 has eye phenotype, non-enhanceable by CycAS054513/CycA[+]
EgfrE1 has eye phenotype, non-enhanceable by DeltaS049520/Dl[+]
EgfrE1 has eye phenotype, non-enhanceable by Mi-2S005504/Mi-2[+]
EgfrE1 has eye phenotype, non-enhanceable by Mi-2S147412/Mi-2[+]
EgfrE1 has eye phenotype, non-enhanceable by Sin3A[+]/Sin3A08269
EgfrE1 has eye phenotype, non-enhanceable by l(3)06906[+]/l(3)0690606906
EgfrE1 has eye phenotype, non-enhanceable by l(3)S000710[+]/l(3)S000710S000710
EgfrE1 has eye phenotype, non-enhanceable by l(3)S000718[+]/l(3)S000718S000718
EgfrE1 has eye phenotype, non-enhanceable by l(3)S009515[+]/l(3)S009515S009515
EgfrE1 has eye phenotype, non-enhanceable by l(3)S012805S012805/l(3)S012805[+]
EgfrE1 has eye phenotype, non-enhanceable by l(3)S016805[+]/l(3)S016805S016805
EgfrE1 has eye phenotype, non-enhanceable by l(3)S019203S141715/l(3)S019203[+]
EgfrE1 has eye phenotype, non-enhanceable by l(3)S023549S023549/l(3)S023549[+]
EgfrE1 has eye phenotype, non-enhanceable by l(3)S023549S090101/l(3)S023549[+]
EgfrE1 has eye phenotype, non-enhanceable by l(3)S023708[+]/l(3)S023708S023708
EgfrE1 has eye phenotype, non-enhanceable by l(3)S023901[+]/l(3)S023901S023901
EgfrE1 has eye phenotype, suppressible by Ptp61F[+]/Ptp61F4-10
EgfrE1 has eye phenotype, suppressible by Ptp61FRNAi.UAS.WIZ/Scer\GAL4GMR.PU
EgfrE1 has eye phenotype, suppressible by mir-998exc222
EgfrE1 has eye disc phenotype, suppressible by mir-998exc222
EgfrE1 has ommatidium phenotype, suppressible by mir-998exc222
EgfrE1 has wing vein | ectopic phenotype, suppressible by Scer\GAL4Act5C.PU/Sulf1UAS.cBa
EgfrE1 has photoreceptor cell R8 of pale ommatidium phenotype, suppressible by sev14/sev14
EgfrE1 has photoreceptor cell R7 of yellow ommatidium phenotype, suppressible by sev14/sev14
EgfrE1 has wing vein L2 phenotype, suppressible by Gl[+]/DCTN1-p150Gl-1
EgfrE1 has eye phenotype, suppressible by bonS048706/bon[+]
EgfrE1 has eye phenotype, suppressible by l(3)j2D5j2D5/l(3)j2D5[+]
EgfrE1 has eye phenotype, suppressible by Scer\GAL4ey.PB/sensUAS.cNa
EgfrE1 has ommatidium phenotype, suppressible by Scer\GAL4ey.PB/sensUAS.cNa
EgfrE1 has ommatidium phenotype, suppressible by klu[+]/kluunspecified
EgfrE1 has wing vein | ectopic phenotype, suppressible by Ras85D[+]/Ras85Dunspecified
EgfrE1 has wing vein | ectopic phenotype, suppressible by Rafunspecified
EgfrE1 has wing vein | ectopic phenotype, suppressible by Stat92Eunspecified/Stat92E[+]
EgfrE1 has eye phenotype, suppressible by Ras85DSutor-341/Ras85D[+]
EgfrE1 has eye phenotype, suppressible by Ras85D[+]/Ras85DSutor-404
EgfrE1 has eye phenotype, suppressible by Sos[+]/SosSutor-157
EgfrE1 has eye phenotype, suppressible by SosSutor-405/Sos[+]
EgfrE1 has eye phenotype, suppressible by Su(tor)1-1[+]/Su(tor)1-1134
EgfrE1 has eye phenotype, suppressible by Su(tor)1-119/Su(tor)1-1[+]
EgfrE1 has eye phenotype, suppressible by Su(tor)2-180[+]/Su(tor)2-1801
EgfrE1 has eye phenotype, suppressible by Su(tor)2-2371/Su(tor)2-237[+]
EgfrE1 has eye phenotype, suppressible by Su(tor)2-278[+]/Su(tor)2-2781
EgfrE1 has eye phenotype, suppressible by Su(tor)2-321[+]/Su(tor)2-3211
EgfrE1 has eye phenotype, suppressible by Su(tor)2-3[+]/Su(tor)2-31
EgfrE1 has eye phenotype, suppressible by Su(tor)2-3[+]/Su(tor)2-3361
EgfrE1 has eye phenotype, suppressible by Su(tor)2-4081/Su(tor)2-408[+]
EgfrE1 has eye phenotype, suppressible by Su(tor)3-1[+]/Su(tor)3-138
EgfrE1 has photoreceptor cell R8 of pale ommatidium phenotype, non-suppressible by rhoPΔ5/rhoPΔ5
EgfrE1 has eye phenotype, non-suppressible by CycAS054513/CycA[+]
EgfrE1 has eye phenotype, non-suppressible by DeltaS049520/Dl[+]
EgfrE1 has eye phenotype, non-suppressible by Mi-2S005504/Mi-2[+]
EgfrE1 has eye phenotype, non-suppressible by Mi-2S147412/Mi-2[+]
EgfrE1 has eye phenotype, non-suppressible by Sin3A[+]/Sin3A08269
EgfrE1 has eye phenotype, non-suppressible by l(3)06906[+]/l(3)0690606906
EgfrE1 has eye phenotype, non-suppressible by l(3)S000710[+]/l(3)S000710S000710
EgfrE1 has eye phenotype, non-suppressible by l(3)S000718[+]/l(3)S000718S000718
EgfrE1 has eye phenotype, non-suppressible by l(3)S009515[+]/l(3)S009515S009515
EgfrE1 has eye phenotype, non-suppressible by l(3)S012805S012805/l(3)S012805[+]
EgfrE1 has eye phenotype, non-suppressible by l(3)S016805[+]/l(3)S016805S016805
EgfrE1 has eye phenotype, non-suppressible by l(3)S019203S141715/l(3)S019203[+]
EgfrE1 has eye phenotype, non-suppressible by l(3)S023549S023549/l(3)S023549[+]
EgfrE1 has eye phenotype, non-suppressible by l(3)S023549S090101/l(3)S023549[+]
EgfrE1 has eye phenotype, non-suppressible by l(3)S023708[+]/l(3)S023708S023708
EgfrE1 has eye phenotype, non-suppressible by l(3)S023901[+]/l(3)S023901S023901
EgfrE1 has eye phenotype, non-suppressible by l(3)S024329S024329/l(3)S024329[+]
EgfrE1 has eye phenotype, non-suppressible by l(3)S024833[+]/l(3)S024833S024833
EgfrE1 has eye phenotype, non-suppressible by l(3)S026238S026238/l(3)S026238[+]
EgfrE1 has eye phenotype, non-suppressible by l(3)S026421S026421/l(3)S026421[+]
EgfrE1 has eye phenotype, non-suppressible by l(3)S046604S046604/l(3)S046604[+]
EgfrE1 has eye phenotype, non-suppressible by l(3)S056113[+]/l(3)S056113S056113
EgfrE1 has eye phenotype, non-suppressible by l(3)S066607[+]/l(3)S066607S066607
EgfrE1 has eye phenotype, non-suppressible by l(3)S068808S068808/l(3)S068808[+]
EgfrE1 has eye phenotype, non-suppressible by l(3)S081003S145911/l(3)S081003[+]
EgfrE1 has eye phenotype, non-suppressible by l(3)S090114[+]/l(3)S090114S090114
EgfrE1 has eye phenotype, non-suppressible by l(3)S092708[+]/l(3)S092708S092708
EgfrE1 has eye phenotype, non-suppressible by l(3)S133117[+]/l(3)S133117S133117
EgfrE1 has eye phenotype, non-suppressible by l(3)S135703S135703/l(3)S135703[+]
EgfrE1 has eye phenotype, non-suppressible by l(3)S142909S142909/l(3)S142909[+]
EgfrE1 has eye phenotype, non-suppressible by l(3)j4B9j4B9/l(3)j4B9[+]
EgfrE1 has eye phenotype, non-suppressible by l(3)j5B6j5B6/l(3)j5B6[+]
EgfrE1 has eye phenotype, non-suppressible by stgS024503/stg[+]
EgfrE1 has wing vein | ectopic phenotype, non-suppressible by Mad[+]/Madunspecified
EgfrE1 has wing vein | ectopic phenotype, non-suppressible by tkvunspecified/tkv[+]
EgfrE1 has wing phenotype, non-suppressible by p38bDN.UAS/Scer\GAL4unspecified
Egfr[+]/EgfrE1 is an enhancer of wing vein | ectopic phenotype of Pi3K68DKD.UAS.Tag:MYC, Scer\GAL469B
Egfr[+]/EgfrE1 is an enhancer of wing vein L1 phenotype of Adv1
Egfr[+]/EgfrE1 is an enhancer of wing vein L2 phenotype of Adv1
EgfrE1 is a non-enhancer of eye phenotype of upd1GMR.PB
EgfrE1 is a non-enhancer of phenotype of Rho1rev220
EgfrE1 is a suppressor of wing vein phenotype of PtpmegUAS.cLa, Scer\GAL4en.PU
EgfrE1 is a suppressor of ommatidium phenotype of hidGMR.PG
EgfrE1 is a non-suppressor of eye phenotype of upd1GMR.PB
EgfrE1 is a non-suppressor of phenotype of Rho1rev220
EgfrE1, sensE2 has ommatidium phenotype
EgfrE1, sensE2 has ommatidium | somatic clone phenotype
EgfrE1, sensE2 has eye | somatic clone phenotype
Egfr[+]/EgfrE1, sensE2 has ommatidium | somatic clone phenotype
Egfr[+]/EgfrE1, sensE2 has eye | somatic clone phenotype
Egfr[+]/EgfrE1, Pi3K68DUAS.Tag:MYC, Scer\GAL469B has anterior crossvein phenotype
Egfr[+]/EgfrE1, Pi3K68DUAS.Tag:MYC, Scer\GAL469B has posterior crossvein phenotype
Df(3R)P14/14-3-3εj2B10, EgfrE1 has photoreceptor cell R8 phenotype
EgfrE1 suppresses the wing vein loss seen when PtpmegScer\UAS.cLa is expressed under the control of Scer\GAL4en.PU.
mir-998exc222 strongly suppresses the reduction in ommatidial cluster number and rough eye phenotype seen in EgfrE1/+ mutant eye discs. When mir-998exc222 mutant clones are induced in EgfrE1 eye discs, the mutant phenotype is partially suppressed in cells immediately adjacent to the clones, suggesting non-cell autonomous effects.
Expression of CG4096KK108644 under the control of Scer\GAL4Act5C.PU enhances the extra wing vein phenotype of EgfrE1 flies.
Expression of Sulf1Scer\UAS.cBa under the control of Scer\GAL4Act5C.PU suppresses the extra wing vein phenotype of EgfrE1 flies.
In EgfrE1/+ adults, the number of ommatidia with pale-type R8 cells and yellow-type R7 cells is significantly increased. Many of these are found in pale-yellow hybrid ommatidia with a yellow-type R7 and a pale-type R8. This phenotype is suppressed by sev14/sev14, but not by rhoPΔ5 homozygous somatic clones.
Adult eyes containing sensE2 homozygous somatic clones induced in an EgfrE1/+ background are smaller than wild-type. Within the clone there are reduced numbers of ommatidia, as well as gaps of tissue between ommatidia, a phenotype similar to that seen in EgfrE1 homozygotes. sensScer\UAS.cNa; Scer\GAL4ey.PB partially rescues eye size and ommatidial number, and completely suppresses the formation of undifferentiated regions in EgfrE1 homozygous adult eyes.
EgfrE1/+ enhances the formation of an ectopic crossvein in flies expressing Pi3K68DKD.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL469B at 25[o]C.
Flies expressing Pi3K68DScer\UAS.T:Hsap\MYC under the control of Scer\GAL469B in a EgfrE1/+ background at 25[o]C show loss of the anterior and partial loss of the posterior crossvein.
kluunspecified/+ suppresses the rough eye phenotype seen in EgfrE1 adults.
The rough eye phenotype of EgfrE1/+ flies is strongly enhanced by homozygosity for kek1unspecified. These flies also have small eyes and more extra vein material than EgfrE1/+ flies.
EgfrE1/+ flies carrying Pp2B-14Dact.GMR and CanBGMR.PS have a rough eye phenotype similar to that caused by Pp2B-14Dact.GMR and CanBGMR.PS in an Egfr+ background.
The number of ommatidia in the eyes of EgfrE1/EgfrE3 adults is not altered if the flies are also expressing BacA\p35GMR.PH, but the number of pigment cells is increased in these animals.
Expression of p38bDN.Scer\UAS under the control of Scer\GAL4unspecified has no significant effect on the wing phenotype caused by EgfrE1.
R8 photoreceptor cells fail to form in EgfrE1/+ ; 14-3-3εj2B10/Df(3R)P14 eye discs.
Enhances the phenotype of E2fGMR.PD DpGMR.PD BacA\p35GMR.PH flies.
The EgfrE1/+ rough eye phenotype is completely suppressed by cora12 or cora15. The EgfrE1/+ phenotype is partially suppressed by cora1, cora2 or cora13; the eye is wild type in size with some roughening. The EgfrE1/+ phenotype is partially suppressed by cora4, cora5, cora6 or cora14; the eye is smaller than wild type with some roughening. The EgfrE1/+ rough eye phenotype is slightly suppressed by cora3, cora7, cora8 or cora10. The EgfrE1/+ rough eye phenotype is not dominantly suppressed by cora9 or cora11.
The EgfrE1/+ rough eye phenotype is strongly dominantly enhanced by vnunspecified.
Eye of double heterozygotes with S1 are dramatically reduced with respect to those of either heterozygote alone. When heterozygous for Df(2L)ast2 (removing S and ast) the reduced phenotype becomes much more pronounced.
Eye phenotype can be suppressed by mutations of spi.
E.H. Grell, Feb. 1957.
Phenotype is highly sensitive to the wild-type genetic background.
Mutations in S suppress the formation of ectopic wing veins in EgfrE1 flies, but enhance the mutant phenotype in the eye.
Rough eye phenotype is dominantly suppressed by cora1 and cora2.