FlyBase Allele Report: Dmel\E2f1[GMR.PD]

General Information

Symbol

Dmel\E2f1^GMR.PD

Species

D. melanogaster

Name

glass multimer reporter construct of Du

FlyBase ID

FBal0048705

Feature type

allele

Associated gene

Dmel\E2f1

Associated Insertion(s)

Carried in Construct

P{GMRdE2F}

Also Known As

GMR-dE2F

Key Links

Transgenic product class

wild_type

(Du et al., 1996)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Du et al., 1996)

Mutagen

in vitro construct

(Du et al., 1996)

Progenitor genotype

Carried in construct

P{GMRdE2F}

Cytology

Description

GMR regulatory sequences drive expression of E2f1.

(Du et al., 1996)

Allele components

Component

Use(s)

Regulatory region(s)

GMR

engineered transcription regulatory region

Encoded product / tool

E2f1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by BacA\p35^GMR.PH

(Kuzin et al., 2000, Du et al., 1996)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by Df(1)AD11/+

(Du and Dyson, 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by Df(1)su(s)83/+

(Du and Dyson, 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by Rbf^120a

(Du and Dyson, 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by Rbf¹⁴

(Du and Dyson, 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by spen^pjc-15

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by spen^pjc-4

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by spen^pjc-15, E2f1^GMR.PD

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by spen^pjc-7, E2f1^GMR.PD

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by spen^pjc-4, E2f1^GMR.PD

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by spen^ksh-1, E2f1^GMR.PD

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by spen^ksh-1

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by spen^ksh-2

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by spen^ksh-3

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by spen^ksh-4

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by E(E2f)2B^pjc-10

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by E(E2f)2B^pjc-1

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by E(E2f)2B^ksh-5

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by brm^pjc-2

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by brm^ksh-6

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by brm^ksh-7

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by brm^ksh-8

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by mor^ksh-9

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by mor^ksh-10

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by osa^pjc-3

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by osa^ksh-11

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by osa^ksh-12

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by osa^ksh-13

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by osa^E65

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by pnt^pjc-6

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by pnt^pjc-5

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by pnt^ksh-14

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by pjc-16^pjc-16

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by ksh-15^ksh-15

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by ksh-16^ksh-16

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by ksh-17^ksh-17

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by ksh-18^ksh-18

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by ksh-19^ksh-19

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by Df(3L)M21

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by Df(3L)HR370

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by Df(2R)Pu-D17

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by Df(1)C128

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by spen^pjc-7

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by osa^E65

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by spen^poc361

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by Egfr^E1

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by rl^Sem

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by Ras85D^e2F

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by Ras85D^e1B

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by pnt^07825Δ78

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by mor¹

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by mor²

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by mor⁵

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by brm²

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by osa²

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, enhanceable by Df(3L)th102

(Staehling-Hampton et al., 1999)

NOT Enhanced by

Statement

Reference

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by E2f1^rM729

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by E2f1⁰⁷¹⁷²

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by Cdk1^E10

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by Cdk1^216A

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by Dp^49Fk-1

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by Df(2R)vg56

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by Df(2R)H81

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by CycA⁵

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by Df(2R)59AB

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by CycE^AR95

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by CycE²

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by stg²

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by stg⁷

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by pnt^05484Δ33

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-enhanceable by Df(3L)brm11

(Staehling-Hampton et al., 1999)

Suppressed by

Statement

Reference

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, suppressible by Nos^GMR.PK

(Kuzin et al., 2000)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, suppressible by Nos^hs.PK

(Kuzin et al., 2000)

Dp^GMR.PD, E2f1^GMR.PD, Rbf^GMR.PD has visible phenotype, suppressible by BacA\p35^GMR.PH

(Kuzin et al., 2000)

NOT suppressed by

Statement

Reference

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by Df(3L)brm11

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by Dp^49Fk-1

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by stg²

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by stg⁷

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by E2f1^rM729

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by E2f1⁰⁷¹⁷²

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by Df(2R)vg56

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by Cdk1^E10

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by Cdk1^216A

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by Df(2R)H81

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by CycA⁵

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by Df(2R)59AB

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by CycE^AR95

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype, non-suppressible by CycE²

(Staehling-Hampton et al., 1999)

Enhancer of

Statement

Reference

spen^pjc-15, E2f1^GMR.PD is an enhancer of visible phenotype of BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD

(Staehling-Hampton et al., 1999)

spen^pjc-7, E2f1^GMR.PD is an enhancer of visible phenotype of BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD

(Staehling-Hampton et al., 1999)

spen^pjc-4, E2f1^GMR.PD is an enhancer of visible phenotype of BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD

(Staehling-Hampton et al., 1999)

spen^ksh-1, E2f1^GMR.PD is an enhancer of visible phenotype of BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD

(Staehling-Hampton et al., 1999)

Suppressor of

Statement

Reference

E2f1^GMR.PD, Scer\GAL4^GMR.PF is a suppressor of visible phenotype of E2f2^UAS.cFa, Scer\GAL4^GMR.PF

(Frolov et al., 2001)

NOT Suppressor of

Statement

Reference

E2f1^GMR.PD is a non-suppressor of visible phenotype of Mmus\Mdm2^UAS.cFa, Scer\GAL4^GMR.PF

(Folberg-Blum et al., 2002)

E2f1^GMR.PD is a non-suppressor of abnormal size | adult stage phenotype of Mmus\Mdm2^UAS.cFa, Scer\GAL4^GMR.PF

(Folberg-Blum et al., 2002)

Other

Statement

Reference

Dp^GMR.PD, E2f1^GMR.PD has visible phenotype

(Kuzin et al., 2000, Du and Dyson, 1999, Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has increased cell death phenotype

(Du et al., 1996)

Dp^GMR.PD, E2f1^GMR.PD has decreased cell number phenotype

(Du et al., 1996)

Dp^GMR.PD, E2f1^GMR.PD has increased occurrence of cell division phenotype

(Du et al., 1996, Du et al., 1996)

Phenotype Manifest In

Enhanced by

Statement

Reference

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has ommatidium phenotype, enhanceable by Nos^{4.GMR.Tag:FLAG}

(Stasiv et al., 2004)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by Nos^{4.GMR.Tag:FLAG}

(Stasiv et al., 2004)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by ebi^CC3

(Boulton et al., 2000)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by ebi^CC4

(Boulton et al., 2000)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by ebi^k16213

(Boulton et al., 2000)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has interommatidial bristle phenotype, enhanceable by ebi^k16213

(Boulton et al., 2000)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has ommatidium phenotype, enhanceable by ebi^k16213

(Boulton et al., 2000)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by ebi^CC1

(Boulton et al., 2000)

Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by BacA\p35^GMR.PH

(Kuzin et al., 2000, Du et al., 1996)

Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by Df(1)AD11/+

(Du and Dyson, 1999)

Dp^GMR.PD, E2f1^GMR.PD has ommatidium phenotype, enhanceable by Df(1)AD11/+

(Du and Dyson, 1999)

Dp^GMR.PD, E2f1^GMR.PD has interommatidial bristle phenotype, enhanceable by Df(1)AD11/+

(Du and Dyson, 1999)

Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by Df(1)su(s)83/+

(Du and Dyson, 1999)

Dp^GMR.PD, E2f1^GMR.PD has ommatidium phenotype, enhanceable by Df(1)su(s)83/+

(Du and Dyson, 1999)

Dp^GMR.PD, E2f1^GMR.PD has interommatidial bristle phenotype, enhanceable by Df(1)su(s)83/+

(Du and Dyson, 1999)

Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by Rbf^120a

(Du and Dyson, 1999)

Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by Rbf¹⁴

(Du and Dyson, 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by spen^pjc-15

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by spen^ksh-1

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by spen^ksh-2

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by spen^ksh-3

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by spen^ksh-4

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by E(E2f)2B^pjc-10

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by E(E2f)2B^pjc-1

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by E(E2f)2B^ksh-5

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by brm^pjc-2

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by brm^ksh-6

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by brm^ksh-7

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by brm^ksh-8

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by mor^ksh-9

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by mor^ksh-10

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by osa^pjc-3

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by osa^ksh-11

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by osa^ksh-12

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by osa^ksh-13

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by osa^E65

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by pnt^pjc-6

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by pnt^pjc-5

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by pnt^ksh-14

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by pjc-16^pjc-16

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by ksh-15^ksh-15

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by ksh-16^ksh-16

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by ksh-17^ksh-17

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by ksh-18^ksh-18

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by ksh-19^ksh-19

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by Df(3L)M21

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by Df(3L)HR370

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by Df(2R)Pu-D17

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by spen^pjc-7

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by Df(1)C128

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by osa^E65

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by spen^poc361

(Staehling-Hampton et al., 1999)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, enhanceable by spen^pjc-4

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has ommatidium phenotype, enhanceable by BacA\p35^GMR.PH

(Du et al., 1996)

Suppressed by

Statement

Reference

Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, suppressible by Nos^GMR.PK

(Kuzin et al., 2000)

Dp^GMR.PD, E2f1^GMR.PD has eye phenotype, suppressible by Nos^hs.PK

(Kuzin et al., 2000)

Dp^GMR.PD, E2f1^GMR.PD, Rbf^GMR.PD has eye phenotype, suppressible by BacA\p35^GMR.PH

(Kuzin et al., 2000)

Dp^GMR.PD, E2f1^GMR.PD, Rbf^GMR.PD has pigment cell phenotype, suppressible by BacA\p35^GMR.PH

(Kuzin et al., 2000)

Suppressor of

Statement

Reference

E2f1^GMR.PD, Scer\GAL4^GMR.PF is a suppressor of eye phenotype of E2f2^UAS.cFa, Scer\GAL4^GMR.PF

(Frolov et al., 2001)

E2f1^GMR.PD, Scer\GAL4^GMR.PF is a suppressor of ommatidium phenotype of E2f2^UAS.cFa, Scer\GAL4^GMR.PF

(Frolov et al., 2001)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD is a suppressor of eye phenotype of Rbf^GMR.PD

(Kuzin et al., 2000)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD is a suppressor of ommatidium phenotype of Rbf^GMR.PD

(Kuzin et al., 2000)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD is a suppressor of pigment cell phenotype of Rbf^GMR.PD

(Kuzin et al., 2000)

NOT Suppressor of

Statement

Reference

E2f1^GMR.PD is a non-suppressor of eye phenotype of Mmus\Mdm2^UAS.cFa, Scer\GAL4^GMR.PF

(Folberg-Blum et al., 2002)

Other

Statement

Reference

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has eye phenotype

(Stasiv et al., 2004)

BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD has ommatidium phenotype

(Stasiv et al., 2004)

Dp^GMR.PD, E2f1^GMR.PD has ommatidium phenotype

(Kuzin et al., 2000, Staehling-Hampton et al., 1999, Du et al., 1996)

Dp^GMR.PD, E2f1^GMR.PD has eye phenotype

(Kuzin et al., 2000, Du and Dyson, 1999, Staehling-Hampton et al., 1999, Du et al., 1996, Du et al., 1996)

Dp^GMR.PD, E2f1^GMR.PD has interommatidial bristle | ectopic phenotype

(Kuzin et al., 2000)

Dp^GMR.PD, E2f1^GMR.PD has interommatidial bristle phenotype

(Staehling-Hampton et al., 1999, Du et al., 1996)

Dp^GMR.PD, E2f1^GMR.PD has eye photoreceptor cell phenotype

(Staehling-Hampton et al., 1999, Du et al., 1996)

Dp^GMR.PD, E2f1^GMR.PD has cone cell phenotype

(Staehling-Hampton et al., 1999, Du et al., 1996, Du et al., 1996)

Dp^GMR.PD, E2f1^GMR.PD, spen^poc361 has interommatidial bristle phenotype

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD, spen^poc361 has eye disc phenotype

(Staehling-Hampton et al., 1999)

Dp^GMR.PD, E2f1^GMR.PD has photoreceptor neuron phenotype

(Du et al., 1996)

Dp^GMR.PD, E2f1^GMR.PD has macrochaeta | increased number phenotype

(Du et al., 1996)

Additional Comments

Genetic Interactions

Statement

Reference

E2f^GMR.PD, Dp^GMR.PD, BacA\p35^GMR.PH animals exhibit extra cells in the adult eye.

(Stasiv et al., 2004)

ebi^k16213 enhances the rough eye phenotype of E2f^GMR.PD Dp^GMR.PD BacA\p35^GMR.PH, increasing the irregular arrangement of the ommatidial facets. A large number of inter-ommatidial bristle duplications are also seen.

(Boulton et al., 2000)

In the eyes of E2f^GMR.PD, Dp^GMR.PD flies ommatidia form irregular rows and lack their regular hexagonal shape. In addition, many eye bristles are duplicated. The addition of Nos^GMR.PK or Nos^hs.PK (with heatshock) to E2f^GMR.PD, Dp^GMR.PD flies the eye phenotypes seen are greatly reduced in severity. The addition of BacA\p35^GMR.PH to E2f^GMR.PD, Dp^GMR.PD flies enhances the eye phenotype seen in these flies. The addition of BacA\p35^GMR.PH suppresses to wild-type the eye phenotype seen in E2f^GMR.PD, Dp^GMR.PD, Rbf^GMR.PD flies. The inhibition of Nos activity with L-NAME prevents this suppression. The arrangement of ommatidia is still abnormal, and many additional pigment cells are still observed.

(Kuzin et al., 2000)

Flies expressing both E2f^GMR.PD and Dp^GMR.PD have a rough eye phenotype, although individual ommatidia are relatively normal. This phenotype is dominantly enhanced by Df(1)AD11 or Df(1)su(s)83; ommatidia are abnormal and variably shaped and additional bristles are seen in places. The phenotype is also enhanced by Rbf^120a or Rbf¹⁴.

(Du and Dyson, 1999)

The eyes of flies expressing both E2f^GMR.PD and Dp^GMR.PD have extra sensory bristles and the regular pattern of bristle, cone and photoreceptor cells is disrupted, causing a rough eye phenotype. The E2f^GMR.PD Dp^GMR.PD phenotype is unaffected if the flies are also carrying Dp^49Fk-1, Df(2R)vg56, E2f^rM729, E2f⁰⁷¹⁷², cdc2^E10, cdc2^216A, Df(2R)H81, CycA⁵, Df(2R)59AB, CycE^AR95, CycE², stg² or stg⁷. The E2f^GMR.PD Dp^GMR.PD phenotype is subtly enhanced by osa^E65 and dramatically enhanced in the presence of both osa^E65 and BacA\p35^GMR.PH.

(Staehling-Hampton et al., 1999)

Flies carrying P{GMRdDP} have almost normal eye structure assayed by SEM, although a few additional bristles can be seen. Cross sections reveal ommatidial structure is normal. Flies carrying two copies of both P{GMRdDP} and P{GMRdE2F} have severely affected eyes. Eyes are rough, ommatidia are misshapen and ectopic interommatidial bristles develop. Approximately 50% of ommatidia have missing photoreceptor cells and 25% have extra photoreceptor cells. The normal symmetrical pattern of photoreceptor trapezoids is not present. The arrangement of cone cells is perturbed, and the number of cone cells per cluster varies between 3 and 5. Neuronal cell differentiation is initiated normally. BrdU staining reveals that ectopic S phases occur posterior to the morphogenetic furrow, sometimes in differentiating cells. Acridine orange staining reveals that increased cell death occurs posterior to the furrow. A significant delay separates the onset of expression of E2f^GMR.PD and Dp^GMR.PD and the onset of apoptosis. This phenotype is enhanced by BacA\p35^GMR.PH.

(Du et al., 1996)

Coexpression of E2f^GMR.PD and Dp^GMR.PD causes ectopic S phases in the regions of the eye that normally contain only postmitotic cells. The eyes of adults carrying two copies of E2f^GMR.PD and Dp^GMR.PD are rough and are characterised by abnormal pattern of photoreceptors and cone cells, and by additional bristles. The mutant eye phenotype caused by Rbf^GMR.PD can be suppressed by coexpression of E2f^GMR.PD and Dp^GMR.PD. Rbf^GMR.PD expression in adults carrying two copies of E2f^GMR.PD and Dp^GMR.PD suppresses the rough eye phenotype, restoring the normal arrangement of ommatidia.

(Du et al., 1996)

Xenogenetic Interactions

Statement

Reference

Co-expression of E2f^GMR.PD does not rescue the eye phenotype caused by expression of Mmus\Mdm2^Scer\UAS.cFa under the control of Scer\GAL4^GMR.PF.

(Folberg-Blum et al., 2002)

(Boulton et al., 2000)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

E2f1^GMR.PD

E2f^GMR.PD

Name Synonyms

glass multimer reporter construct of Du

(Du et al., 1996)

Secondary FlyBase IDs

References (10)

Report Sections

Open Close