FlyBase Allele Report: Dmel\AdamTS-B[KK108644]

General Information

Symbol

Dmel\AdamTS-B^KK108644

Species

D. melanogaster

Name

FlyBase ID

FBal0235709

Feature type

allele

Associated gene

Dmel\AdamTS-B

Associated Insertion(s)

Carried in Construct

P{KK108644}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK108644}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK108644

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^Act5C.PU

(Butchar et al., 2012)

visible | adult stage, with Scer\GAL4^Bx-MS1096

(Pham et al., 2018)

Phenotype Manifest In

posterior crossvein, with Scer\GAL4^Bx-MS1096

(Pham et al., 2018)

wing, with Scer\GAL4^Act5C.PU

(Butchar et al., 2012)

wing vein | ectopic, with Scer\GAL4^Act5C.PU

(Butchar et al., 2012)

wing vein L2 | ectopic, with Scer\GAL4^Bx-MS1096

(Pham et al., 2018)

Detailed Description

Statement

Reference

Expression of AdamTS-B^KK108644 under the control of Scer\GAL4^Bx-MS1096 leads to either an extra branch on the posterior crossvein (PCV) or a delta at the PCV compared to controls.

(Pham et al., 2018)

Expression of CG4096^KK108644 under the control of Scer\GAL4^Act5C.PU results in an extra vein phenotype with an additional vin fragment above vein L2 and some vein deltas and a reduction in wing size.

(Butchar et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, suppressible by Ras85D^e1B

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, suppressible | partially by spi¹/Krn²⁷

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, suppressible | partially by vn^L6/Krn²⁷

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, suppressible by spi¹/vn^L6/Krn²⁷

(Butchar et al., 2012)

NOT suppressed by

Statement

Reference

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, non-suppressible by Krn²⁷

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, non-suppressible by spi¹/vn^L6

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, non-suppressible by Df(2R)Egfr3

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, non-suppressible by pnt^Δ88

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, non-suppressible by spi¹

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, non-suppressible by vn^ddd-3

(Butchar et al., 2012)

Enhancer of

Statement

Reference

Scer\GAL4^Act5C.PU/AdamTS-B^KK108644 is an enhancer of visible phenotype of Egfr^E1

(Butchar et al., 2012)

Phenotype Manifest In

Suppressed by

Statement

Reference

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has wing vein | ectopic phenotype, suppressible by Ras85D^e1B

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has wing vein | ectopic phenotype, suppressible | partially by spi¹/Krn²⁷

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has wing vein | ectopic phenotype, suppressible | partially by vn^L6/Krn²⁷

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has wing vein | ectopic phenotype, suppressible by spi¹/vn^L6/Krn²⁷

(Butchar et al., 2012)

NOT suppressed by

Statement

Reference

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has wing vein | ectopic phenotype, non-suppressible by Df(2R)Egfr3

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has wing vein | ectopic phenotype, non-suppressible by pnt^Δ88

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has wing vein | ectopic phenotype, non-suppressible by spi¹

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has wing vein | ectopic phenotype, non-suppressible by vn^ddd-3

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has wing vein | ectopic phenotype, non-suppressible by Krn²⁷

(Butchar et al., 2012)

AdamTS-B^KK108644, Scer\GAL4^Act5C.PU has wing vein | ectopic phenotype, non-suppressible by spi¹/vn^L6

(Butchar et al., 2012)

Enhancer of

Statement

Reference

Scer\GAL4^Act5C.PU/AdamTS-B^KK108644 is an enhancer of wing vein | ectopic phenotype of Egfr^E1

(Butchar et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of CG4096^KK108644 under the control of Scer\GAL4^Act5C.PU enhances the extra wing vein phenotype of Egfr^E1 flies.

The extra wing vein phenotype caused by expression of CG4096^KK108644 under the control of Scer\GAL4^Act5C.PU is not suppressed if the flies also carry one of Df(2R)Egfr3, pnt^Δ88, spi¹, vn^ddd-3 or Krn²⁷.

The extra wing vein phenotype caused by expression of CG4096^KK108644 under the control of Scer\GAL4^Act5C.PU is not suppressed if the flies also simultaneously carry vn^L6 and spi¹.

The extra wing vein phenotype caused by expression of CG4096^KK108644 under the control of Scer\GAL4^Act5C.PU is significantly suppressed if the flies also carry Ras85D^e1B.

The extra wing vein phenotype caused by expression of CG4096^KK108644 under the control of Scer\GAL4^Act5C.PU is significantly suppressed if the also simultaneously carry both spi¹ and Krn²⁷, or both vn^L6 and Krn²⁷. The suppression is more pronounced if the flies simultaneously carry spi¹, Krn²⁷ and vn^L6.

(Butchar et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v108353

P{KK108644}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

AdamTS-B^KK108644

CG4096^KK108644

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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