FB2024_03 , released June 25, 2024
Allele: Scer\GAL4238Y
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General Information
Symbol
Scer\GAL4238Y
Species
S. cerevisiae
Name
FlyBase ID
FBal0048769
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{GawB}238Y
Carried in Construct
Also Known As
238Y, 238Y-GAL4
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Yang et al., 1995)
Progenitor genotype
Associated Insertion(s)
P{GawB}238Y
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{GawB}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      No Assay Recorded
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      adult mushroom body | restricted
      (Yeh et al., 1995)
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 4
      yolk
      (Kim et al., 2007)
      embryonic stage 13 -- 17
      neuroblast of mushroom body | subset
      (Tettamanti et al., 1997)
      embryonic stage 13 -- adult stage
      Kenyon cell
      (Noveen et al., 2000)
      mushroom body neuroblast
      (Noveen et al., 2000)
      embryonic stage 14 -- 17
      neuroblast

      Comment: Expression is in a subset of 4 anterior mushroom body neuroblasts.

      (Kurusu et al., 2002)
      larval stage
      adult mushroom body alpha-lobe | restricted
      (Tettamanti et al., 1997)
      mushroom body calyx
      (Tettamanti et al., 1997)
      Kenyon cell | subset
      (Tettamanti et al., 1997)
      adult mushroom body gamma-lobe | restricted
      (Tettamanti et al., 1997)
      adult mushroom body alpha'-lobe | restricted
      (Tettamanti et al., 1997)
      mushroom body pedunculus
      (Tettamanti et al., 1997)
      adult mushroom body beta-lobe | restricted
      (Tettamanti et al., 1997)
      embryonic/larval mushroom body
      (Kurusu et al., 2002)
      third instar larval stage
      embryonic/larval mushroom body
      (Takaesu et al., 2012, Armstrong et al., 1998)
      inner layer of the larval mushroom body
      (Pauls et al., 2010, Pauls et al., 2010)
      outer layer of the larval mushroom body
      (Pauls et al., 2010, Pauls et al., 2010)
      core layer of the larval mushroom body
      (Pauls et al., 2010, Pauls et al., 2010)
      surface layer of the larval mushroom body
      (Pauls et al., 2010, Pauls et al., 2010)
      pupal stage P5
      adult mushroom body alpha-lobe
      (Armstrong et al., 1998)
      adult mushroom body beta-lobe
      (Armstrong et al., 1998)
      pupal stage P5 -- P7
      mushroom body
      (Armstrong et al., 1998)
      pupal stage P6 | restricted
      adult mushroom body alpha-lobe
      (Armstrong et al., 1998)
      adult mushroom body beta-lobe
      (Armstrong et al., 1998)
      pupal stage P6 -- P7
      adult mushroom body gamma-lobe
      (Armstrong et al., 1998)
      adult mushroom body alpha'-lobe

      Comment: Authors refer to the alpha'-lobe as the 'delta lobe'.

      (Armstrong et al., 1998)
      pupal stage P7
      adult mushroom body alpha-lobe
      (Armstrong et al., 1998)
      adult mushroom body beta-lobe
      (Armstrong et al., 1998)
      adult stage
      adult ventral nerve cord
      (Connolly et al., 1996)
      adult brain | restricted
      (Connolly et al., 1996)
      ellipsoid body
      (Zars et al., 2000)
      adult mushroom body alpha-lobe
      (Tan et al., 2010, Armstrong et al., 1998)
      adult mushroom body beta-lobe
      (Tan et al., 2010, Armstrong et al., 1998)
      extrinsic neuron

      Comment: Authors refer to gamma-lobe exit (MB output) neurons.

      (Armstrong et al., 1998)
      adult mushroom body | restricted
      (Bushey et al., 2009, Zars et al., 2000, Tettamanti et al., 1997)
      adult mushroom body
      (Armstrong et al., 1998, Connolly et al., 1996)
      adult antennal lobe
      (Zars et al., 2000)
      adult mushroom body gamma-lobe
      (Pauls et al., 2010, Tan et al., 2010, Aso et al., 2009, Zars et al., 2000, Armstrong et al., 1998)
      adult mushroom body beta'-lobe
      (Pauls et al., 2010, Tan et al., 2010)
      adult mushroom body alpha'-lobe
      (Pauls et al., 2010, Tan et al., 2010, Armstrong et al., 1998)
      mushroom body beta lobe core layer | intense
      (Aso et al., 2009)
      mushroom body alpha lobe core layer | intense
      (Aso et al., 2009)
      mushroom body beta lobe surface layer | intense
      (Aso et al., 2009)
      mushroom body alpha lobe surface layer | intense
      (Aso et al., 2009)
      mushroom body beta lobe posterior layer | intense
      (Aso et al., 2009)
      mushroom body alpha lobe posterior layer | intense
      (Aso et al., 2009)
      mushroom body beta' anterior-posterior layer
      (Aso et al., 2009)
      mushroom body alpha' middle layer
      (Aso et al., 2009)
      mushroom body beta' middle layer
      (Aso et al., 2009)
      mushroom body alpha' anterior-posterior layer
      (Aso et al., 2009)
      medulla
      (Aso et al., 2009)
      adult protocerebrum | restricted
      (Aso et al., 2009)
      adult lateral horn | faint
      (Aso et al., 2009)
      adult antennal nerve | faint
      (Aso et al., 2009)
      adult deutocerebrum | faint
      (Aso et al., 2009)
      adult tritocerebrum
      (Aso et al., 2009)
      adult gnathal ganglion
      (Aso et al., 2009)
      glial cell of adult brain
      (Aso et al., 2009)
      alpha/beta Kenyon cell
      (Pauls et al., 2010)
      gamma Kenyon cell
      (Pauls et al., 2010)
      alpha'/beta' Kenyon cell
      (Pauls et al., 2010)
      adult pars intercerebralis
      (Aso et al., 2009, Connolly et al., 1996)
      adult mushroom body alpha-lobe
      (Pauls et al., 2010)
      adult mushroom body beta-lobe
      (Pauls et al., 2010)
      Additional Information
      Statement
      Reference

      Drives expression in the mushroom body. Drives expression in mushroom body neuroblasts from embryonic stage 14.

      (FlyBase Curators, 2017)

      Expression becomes prominent at embryonic stage 14 in a subset of 4 mushroom body neuroblasts

      (Kurusu et al., 2002)

      ScerGAL4238Y expresses within a group of neurons connecting the tip of the gamma-lobe to the rostral area of the medial protocerebrum.

      (Armstrong et al., 1998)

      Alpha-lobe and beta-lobe expression of ScerGAL4238Y is extensive in early- and late-pupal and adult stages, but restricted in the mid-pupal stage.

      (Armstrong et al., 1998)

      Embryonic expression is observed in two of the four mushroom body neuroblasts and in their Kenyon cell progeny. Larval expression is observed in two Kenyon cell clusters, in the calyx, in the cap and ring of the α and α' lobes, in the β and γ lobes, and the in the circumference of the pedunculus of the mushroom body.

      (Tettamanti et al., 1997)

      Expression in adult brain primarily in corpora pedunculata (mushroom body).

      (Connolly et al., 1996)
       
      Marker for
      antennal lobe
      (Zars et al., 2000)
      ellipsoid body
      (Zars et al., 2000)
      mushroom body
      (Kurusu et al., 2002, Zars et al., 2000)
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Suppressor of
      NOT Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      238Y
      (DeZazzo et al., 2000)
      GAL4238Y
      Scer\GAL4238Y
      Name Synonyms
      Secondary FlyBase IDs
        References (52)