FB2024_03 , released June 25, 2024
Allele: Scer\GAL4sca.PC
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General Information
Symbol
Scer\GAL4sca.PC
Species
S. cerevisiae
Name
scabrous promoter construct of Chiba
FlyBase ID
FBal0058756
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{sca-Gal-4}
Also Known As
Sca-GAL4, scabrous-Gal4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Budnik et al., 1996)
Progenitor genotype
Carried in construct
P{sca-Gal-4}
Cytology
Description

sca promoter regulates expression of a GAL4 driver.

(Budnik et al., 1996)
Allele components
Component
Use(s)
Regulatory region(s)
sca
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      sensory neuron
      (Budnik et al., 1996)
      epithelial cell
      (Budnik et al., 1996)
      motor neuron
      (Budnik et al., 1996)
      presumptive embryonic/larval nervous system
      (Zlatic et al., 2003)
      embryonic stage 8
      ventral neurectoderm
      (Trébuchet et al., 2019)
      first instar larval stage
      bouton
      (Budnik et al., 1996)
      motor neuron
      (Budnik et al., 1996)
      sensory neuron
      (Budnik et al., 1996)
      epithelial cell
      (Budnik et al., 1996)
      P-stage
      external sensory organ precursor cell
      (Langevin et al., 2005)
      Additional Information
      Statement
      Reference

      Drives expression in the presumptive embryonic/larval nervous system, in sensory and motor neurons in late embryos and early larvae, and in pupal sensory organ precursor cells.

      (FlyBase Curators, 2017)

      In first instar larva, expression observed at the body wall muscle at Type I synaptic boutons.

      (Budnik et al., 1996)
       
      Marker for
      Reflects expression of
      sca
      (Trébuchet et al., 2019, Zlatic et al., 2003, Budnik et al., 1996)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class

      abnormal neuroanatomy, with Ras85DUAS.cKa

      (Koh et al., 2002)

      abnormal neurophysiology, with CspGD10571, Scer\GAL4C57, Scer\GAL4elav-C155

      (Brusich et al., 2015)

      abnormal neurophysiology, with GluRIICRNAi.UAS.cBa, Scer\GAL4C57, Scer\GAL4elav-C155

      (Brusich et al., 2015)

      abnormal neurophysiology, with Scer\GAL4C57, Scer\GAL4elav-C155, cacKK101478

      (Brusich et al., 2015)

      abnormal neurophysiology, with Scer\GAL4elav-C155, cacKK101478

      (Brusich et al., 2015)

      abnormal neurophysiology | larval stage | drug conditional, with Scer\GAL4elav-C155, SnapinGD12574

      (Dickman et al., 2012)

      abnormal neurophysiology | third instar larval stage, with CskUAS.YFP, Scer\GAL4C57, Scer\GAL4elav-C155

      (Spring et al., 2016)

      abnormal neurophysiology | third instar larval stage, with GluRIICRNAi.UAS.cBa, Scer\GAL4C57, Scer\GAL4elav-C155

      (Spring et al., 2016)

      majority die during pharate adult stage | heat sensitive, with Hdac.UAS

      (Nagel and Preiss, 2014)

      majority die during pharate adult stage | heat sensitive, with Hdko.UAS

      (Nagel and Preiss, 2014)

      majority die during pharate adult stage | heat sensitive, with HUAS.cMa

      (Nagel and Preiss, 2014)

      partially lethal - majority die | heat sensitive, with Hdac.UAS

      (Nagel and Preiss, 2014)

      partially lethal - majority die | heat sensitive, with Hdko.UAS

      (Nagel and Preiss, 2014)

      partially lethal - majority die | heat sensitive, with HUAS.cMa

      (Nagel and Preiss, 2014)

      visible, with Hdac.UAS

      (Nagel and Preiss, 2014)

      visible, with Hdko.UAS

      (Nagel and Preiss, 2014)

      visible, with HUAS.cMa

      (Nagel and Preiss, 2014)
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      GAL4sca.PC
      Scer\GAL4sca.PC
      Name Synonyms
      scabrous promoter construct of Chiba
      (Budnik et al., 1996)
      Secondary FlyBase IDs
        References (25)