eye photoreceptor cell & axon, with Scer\GAL4GMR.PF
microchaeta & scutum, with Scer\GAL4ap-md544
photoreceptor cell R1 & axon, with Scer\GAL4GMR.PF
photoreceptor cell R2 & axon, with Scer\GAL4GMR.PF
photoreceptor cell R3 & axon, with Scer\GAL4GMR.PF
photoreceptor cell R4 & axon, with Scer\GAL4GMR.PF
photoreceptor cell R5 & axon, with Scer\GAL4GMR.PF
photoreceptor cell R6 & axon, with Scer\GAL4GMR.PF
photoreceptor cell R7 & axon, with Scer\GAL4GMR.PF
photoreceptor cell R8 & axon, with Scer\GAL4GMR.PF
Expression via Scer\GAL4fkh.PH results in a weakly penetrant 'too wide and lumpy lumen' phenotype in the embryonic salivary gland.
Expression of msnEP549 under the control of Scer\GAL4GMR.PF has no affect on the eye.
In larvae expressing msnEP549 under the control of Scer\GAL4GMR.PF, nay R1-R6 growth cones terminate before they reach the lamina plexus. The regular array of R7 and R8 growth cones in the medulla is also disorganised. This phenotype is fully penetrant.
Mutant larvae expressing msnEP549 under the control of Scer\GAL4elav-C155 have ISN neuron pathfinding defects.
msnEP549 flies, when driven by Scer\GAL4ap-md544 show abnormal orientation of the microchaetae on the notum, wing hair polarity defects are also seen, along with duplication or triplication of some hairs. Over expression of msnEP549 in the eye driven by Scer\GAL4hs.2sev causes a rough eye phenotype and reveal typical polarity defects in ommatidia. Also some ommatidia have missing or malformed photoreceptors.
Expression of msnEP549 under the control of Scer\GAL4GMR.PF causes a large number of R1-R6 photoreceptor cell growth cones to stop before they reach their normal target lamina. Defects are also seen in the medulla terminal field. The shape of the photoreceptor cells and their localisation on the developing eye disc is unaffected.
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, enhanceable by Cdc42unspecified
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, enhanceable by NrtM54
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, non-enhanceable by Rho1E3.10
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, non-enhanceable by bsk1/bsk[+]
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, non-enhanceable by chic01320
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, non-enhanceable by Pakunspecified
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, non-enhanceable by Rac1J11/Rac2Δ/MtlΔ
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, non-enhanceable by dock3
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, non-enhanceable by Df(3L)Ar14-8
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, non-enhanceable by Rho172O
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, suppressible by bif[+]/bifR47
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, suppressible by bifR38/bif[+]
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, suppressible by bsk2/bsk[+]
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, suppressible by hep[+]/hepr75
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, suppressible by JraIA109/Jra[+]
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, suppressible by Df(1)H6/+
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, suppressible by Df(1)G24/+
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, suppressible by Df(2L)flp170B/+
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, suppressible by Df(3R)crb87-4/+
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, suppressible by Df(2L)b80e3/+
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, suppressible by Df(3R)p13/+
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, suppressible by Df(3R)crb-F89-4/+
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, suppressible by Df(2L)b87e25/+
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, non-suppressible by Pakunspecified
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, non-suppressible by Rac1J11/Rac2Δ/MtlΔ
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, non-suppressible by Rho1E3.10
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, non-suppressible by bsk1/bsk[+]
Scer\GAL4GMR.PF, msnEP549 has abnormal neuroanatomy phenotype, non-suppressible by chic01320
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, non-suppressible by dock3
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, non-suppressible by Df(3L)Ar14-8
Scer\GAL4hs.2sev, msnEP549 has abnormal planar polarity phenotype, non-suppressible by Rho172O
msnEP549, Scer\GAL4GMR.PF is an enhancer of visible phenotype of Ppt1UAS.cKa, Scer\GAL4GMR.PF
msnEP549/Scer\GAL4sca-537.4 is an enhancer of visible phenotype of Rala35d
msnEP549, Scer\GAL4GMR.PF is an enhancer of visible phenotype of HUAS.cMa, Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, enhanceable by Cdc42unspecified
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, enhanceable by NrtM54
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, non-enhanceable by Rho1E3.10
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, non-enhanceable by bsk1/bsk[+]
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, non-enhanceable by chic01320
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, non-enhanceable by Pakunspecified
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, non-enhanceable by Rac1J11/Rac2Δ/MtlΔ
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, non-enhanceable by dock3
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, non-enhanceable by Df(3L)Ar14-8
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, non-enhanceable by Rho172O
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, suppressible by bifR38/bif[+]
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, suppressible by bif[+]/bifR47
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, suppressible by bsk2
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, suppressible by hepr75
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, suppressible by JraIA109
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, suppressible by Df(1)H6
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, suppressible by Df(1)G24
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, suppressible by Df(2L)flp170B
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, suppressible by Df(3R)crb87-4
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, suppressible by Df(2L)b80e3
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, suppressible by Df(3R)p13
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, suppressible by Df(3R)crb-F89-4
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, suppressible by Df(2L)b87e25
Scer\GAL4GMR.PF, msnEP549 has eye photoreceptor cell & axon phenotype, suppressible by Scer\GAL4GMR.PF/dockUAS.cRa
Scer\GAL4GMR.PF, msnEP549 has eye photoreceptor cell & axon phenotype, suppressible by dockW225K.UAS/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, msnEP549 has eye photoreceptor cell & axon phenotype, suppressible | partially by dockW48K.UAS/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, non-suppressible by Pakunspecified
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, non-suppressible by Rac1J11/Rac2Δ/MtlΔ
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, non-suppressible by Rho1E3.10
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, non-suppressible by bsk1/bsk[+]
Scer\GAL4GMR.PF, msnEP549 has photoreceptor cell & axon phenotype, non-suppressible by chic01320
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, non-suppressible by dock3
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, non-suppressible by Df(3L)Ar14-8
Scer\GAL4hs.2sev, msnEP549 has ommatidium phenotype, non-suppressible by Rho172O
Scer\GAL4GMR.PF, msnEP549 has eye photoreceptor cell & axon phenotype, non-suppressible by dockW151K.UAS/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, msnEP549 has eye photoreceptor cell & axon phenotype, non-suppressible by Scer\GAL4GMR.PF/dockR336Q.UAS
msnEP549, Scer\GAL4GMR.PF is an enhancer of eye phenotype of Ppt1UAS.cKa, Scer\GAL4GMR.PF
msnEP549/Scer\GAL4sca-537.4 is an enhancer of microchaeta phenotype of Rala35d
msnEP549/Scer\GAL4sca-537.4 is an enhancer of macrochaeta phenotype of Rala35d
msnEP549, Scer\GAL4GMR.PF is an enhancer of eye phenotype of HUAS.cMa, Scer\GAL4GMR.PF
msnEP549/Scer\GAL4GMR.PF is a suppressor of eye photoreceptor cell & axon phenotype of dock04723
msnEP549/Scer\GAL4GMR.PF is a suppressor of eye photoreceptor cell & growth cone phenotype of dock04723
The defects in photoreceptor cell projection patterns seen in larvae overexpressing msnEP549 under the control of Scer\GAL4GMR.PF are largely suppressed by one copy of bifR38 or one copy of bifR47. The defects in photoreceptor cell projection patterns seen in larvae overexpressing msnEP549 under the control of Scer\GAL4GMR.PF are not affected by one copy of bsk1. The defects in photoreceptor cell projection patterns seen in larvae overexpressing msnEP549 under the control of Scer\GAL4GMR.PF are enhanced by Cdc42unspecified or NrtM54. The phenotype caused by expression of msnEP549 under the control of Scer\GAL4GMR.PF is not modified by the addition of Pakunspecified, Rho1E3.10 or chic01320. The phenotype caused by expression of msnEP549 under the control of Scer\GAL4GMR.PF is not modified by the addition of the triple mutant combination Rac1J11 Rac2Δ MtlΔ.
The phenotypes caused by over-expression of msnEP549 in the eye driven by Scer\GAL4hs.2sev are dominantly suppressed by bsk2, hepr75, JraIA109, Df(1)H6, Df(1)G24, Df(2L)flp170B, Df(3R)crb87-4, Df(2L)b80e3, Df(3R)p13, Df(3R)crb-F89-4 and Df(2L)b87e25, leading to almost wild-type ommatidial arrays. The addition of dock3, Df(3L)Ar14-8 and Rho172O have no effect.
Co-expression of dockScer\UAS.cRa or dockW225K.Scer\UAS suppresses the pretarget termination phenotype of photoreceptor cell axons caused by expression of msnEP549 under the control of Scer\GAL4GMR.PF. Co-expression of dockW48K.Scer\UAS weakly suppresses the pretarget termination phenotype of photoreceptor cell axons caused by expression of msnEP549 under the control of Scer\GAL4GMR.PF. Co-expression of dockW151K.Scer\UAS or dockR336Q.Scer\UAS does not suppress the pretarget termination phenotype of photoreceptor cell axons caused by expression of msnEP549 under the control of Scer\GAL4GMR.PF. The dock04723 phenotype is largely suppressed by msnEP549 expressed under the control of Scer\GAL4GMR.PF. The premature termination of many photoreceptor cell growth cones within the optic stalk is also seen in these larvae (this phenotype is not seen in larvae expressing msnEP549 under the control of Scer\GAL4GMR.PF in a wild-type background).
Selected as: an insertion line that modifies the eye phenotype caused by expression of Ppt1Scer\UAS.cKa under the control of Scer\GAL4GMR.PF when co-expressed using Scer\GAL4GMR.PF.