FB2024_04 , released June 25, 2024
Allele: Cnoc\ChR1::CsubChRCsChrimson.IVS.20xUAS.Venus
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General Information
Symbol
Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus
Species
C. noctigama
Name
FlyBase ID
FBal0351548
Feature type
allele
Associated gene
Cnoc\ChR1::Csub\ChR
Associated Insertion(s)
Carried in Construct
P{20XUAS-IVS-CsChrimson.mVenus}
TI{20XUAS-IVS-CsChrimson.mVenus}
Also Known As
UAS-CsChrimson, 20XUAS-CsChrimson-mVenus, 20XUAS-IVS-CsChrimson.mVenus, UAS-Chrimson, UAS-CsChrimson::mVenus, UAS-CsChrimson-mVenus, UAS-CsChrimson.mVenus, CsChrimson, UAS-IVS-CsChrimson.mVenus, 20xUAS-CsChrimson
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Klapoetke et al., 2014)
Progenitor genotype
Carried in construct
P{20XUAS-IVS-CsChrimson.mVenus}
TI{20XUAS-IVS-CsChrimson.mVenus}
Cytology
Description

20xUAS drives expression of CsChrimson fused to Venus. Golgi and ER export motifs have also been added to the coding sequence. FlyBase curator comment: the original published version of FBrf0224260 erroneously stated that this construct contained Chrimson rather than CsChrimson; this has since been corrected in the online published version (for details see also the corrigendum FBrf0226484 and the addendum FBrf0227011).

(Klapoetke et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
CsChrimson
Tagged with
Venus
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class

      abnormal behavior | adult stage | conditional, with Hsap\RELAAD.ple, Scer\GAL4DBD.R72B05

      (Takemura et al., 2017)

      abnormal behavior | adult stage | conditional, with Hsap\RELAAD.R14C08, Scer\GAL4DBD.R15B01

      (Lewis et al., 2015)

      abnormal behavior | adult stage | conditional, with Hsap\RELAAD.R15A01, Scer\GAL4DBD.R71G01

      (Hoopfer et al., 2015)

      abnormal behavior | adult stage | conditional, with Hsap\RELAAD.R52H03, Scer\GAL4DBD.ple

      (Takemura et al., 2017)

      abnormal behavior | adult stage | conditional, with Hsap\RELAAD.R58E02, Scer\GAL4DBD.R18D09

      (Lewis et al., 2015)

      abnormal behavior | adult stage | conditional, with Hsap\RELAAD.R58E02, Scer\GAL4DBD.R22E04

      (Lewis et al., 2015)

      abnormal behavior | adult stage | conditional, with Hsap\RELAAD.R58E02, Scer\GAL4DBD.R93A09

      (Lewis et al., 2015)

      abnormal behavior | adult stage | conditional, with Hsap\RELAAD.R58E02, Scer\GAL4DBD.R93G08

      (Lewis et al., 2015)

      abnormal behavior | adult stage | conditional, with Hsap\RELAAD.R76F05, Scer\GAL4DBD.R23C12

      (Lewis et al., 2015)

      abnormal behavior | adult stage | conditional, with Hsap\RELAAD.R76F05, Scer\GAL4DBD.R80G12

      (Lewis et al., 2015)

      abnormal behavior | adult stage | conditional, with Hsap\RELAAD.VT026773, Scer\GAL4DBD.R72B05

      (Takemura et al., 2017)

      abnormal behavior | larval stage | conditional, with Hsap\RELAAD.R12C11, Scer\GAL4DBD.R20G03

      (Takagi et al., 2017)

      abnormal chemosensory behavior | adult stage | conditional, with Scer\GAL4Gr64f.9.7

      (Sánchez-Alcañiz et al., 2017)

      abnormal chemosensory behavior | adult stage | conditional, with Scer\GAL4VT031497

      (Klapoetke et al., 2014)

      abnormal courtship behavior | adult stage | conditional, with Hsap\RELAAD.R35D04, Scer\GAL4DBD.VT043656

      (Ribeiro et al., 2018)

      abnormal courtship behavior | conditional, with Hsap\RELAAD.R15A01, Scer\GAL4DBD.R71G01

      (Hoopfer et al., 2015)

      abnormal courtship behavior | male, with Scer\GAL4Ir52a.PK

      (He et al., 2019)

      abnormal courtship behavior | male limited | conditional, with Hsap\RELAAD.R15A01, Scer\GAL4DBD.R71G01

      (Kallman et al., 2015)

      abnormal feeding behavior | adult stage | conditional, with Scer\GAL4Crz.391

      (Zer-Krispil et al., 2018)

      abnormal feeding behavior | adult stage | conditional, with Scer\GAL4GMR58H01

      (Zhou et al., 2019)

      abnormal feeding behavior | adult stage | conditional, with Scer\GAL4Gr28b.b.4.7

      (Zhan et al., 2016)

      abnormal feeding behavior | adult stage | conditional, with Scer\GAL4Gr66a.1.8

      (Zhou et al., 2019)

      abnormal feeding behavior | adult stage | conditional, with Scer\GAL4Gr66a.1.8, Scer\GAL4nompC.PC

      (Zhou et al., 2019)

      abnormal feeding behavior | adult stage | conditional, with Scer\GAL4nompC.PC

      (Zhou et al., 2019)

      abnormal feeding behavior | adult stage | conditional, with Scer\GAL4NP7506

      (Zhou et al., 2019)

      abnormal flight | conditional, with Scer\FLP1FLPo.oc.Tag:NLS(SV40-largeT), Scer\GAL4Tdc2.PC, Scer\GAL80FRT.αTub84B

      (O'Sullivan et al., 2018)

      abnormal flight | conditional, with Scer\GAL4GMR42H07

      (O'Sullivan et al., 2018)

      abnormal flight | conditional, with Scer\GAL4Tdc2.PC

      (O'Sullivan et al., 2018)

      abnormal grooming behavior | adult stage | conditional, with Hsap\RELAAD.R42B02, Scer\GAL4DBD.VT037574

      (Cande et al., 2018)

      abnormal grooming behavior | conditional, with Hsap\RELAAD.R11B11, Scer\GAL4DBD.R34C03

      (Hampel et al., 2015)

      abnormal grooming behavior | conditional, with Hsap\RELAAD.R18C11, Scer\GAL4DBD.R71D01

      (Hampel et al., 2015)

      abnormal grooming behavior | conditional, with Hsap\RELAAD.R24C08, Scer\GAL4DBD.R26B12

      (Hampel et al., 2015)

      abnormal grooming behavior | conditional, with Hsap\RELAAD.R30B01, Scer\GAL4DBD.R31H10

      (Hampel et al., 2017)

      abnormal grooming behavior | conditional, with Hsap\RELAAD.R31H10, Scer\GAL4DBD.R34E03

      (Hampel et al., 2017)

      abnormal grooming behavior | conditional, with Hsap\RELAAD.R52F12, Scer\GAL4DBD.R60E02

      (Hampel et al., 2015)

      abnormal grooming behavior | conditional, with Hsap\RELAAD.R76F12, Scer\GAL4DBD.R18C11

      (Hampel et al., 2015)

      abnormal grooming behavior | conditional, with Scer\GAL4GMR30B01

      (Hampel et al., 2017)

      abnormal grooming behavior | conditional, with Scer\GAL4GMR31H10

      (Hampel et al., 2017)

      abnormal grooming behavior | conditional, with Scer\GAL4GMR52A06

      (Hampel et al., 2017)

      abnormal grooming behavior | conditional, with Scer\GAL4GMR81E10

      (Hampel et al., 2017)

      abnormal grooming behavior | conditional, with Scer\GAL4NP1245

      (Hampel et al., 2015)

      abnormal grooming behavior | conditional, with Scer\GAL4NP6250

      (Hampel et al., 2015)

      abnormal grooming behavior | conditional, with Scer\GAL4NP6303

      (Hampel et al., 2015)

      abnormal locomotor behavior | adult stage, with Scer\GAL4Or59b.PC

      (Badel et al., 2016)

      abnormal locomotor behavior | adult stage | conditional, with Ecol\lexAChAT-MI04508-TlexA:QFAD.0, Scer\GAL40273-G4, Scer\GAL80IVS.WPRE.8xlexAop

      (Stern et al., 2019)

      abnormal locomotor behavior | adult stage | conditional, with Ecol\lexAGMR61H03, Scer\GAL40273-G4, Scer\GAL80IVS.WPRE.8xlexAop

      (Stern et al., 2019)

      abnormal locomotor behavior | adult stage | conditional, with Ecol\lexAp65.Trhn, Scer\GAL40273-G4, Scer\GAL80IVS.WPRE.8xlexAop

      (Stern et al., 2019)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R14A01, Scer\GAL4DBD.R79H02

      (von Reyn et al., 2017)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R14C08, Hsap\RELAAD.R30E08, Scer\GAL4DBD.R15B01, Scer\GAL4DBD.R53C10

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R14C08, Scer\GAL4DBD.R15B01

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R15A01, Scer\GAL4DBD.R71G01

      (Hoopfer et al., 2015)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R17A04, Scer\GAL4DBD.R68A06

      (von Reyn et al., 2017)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R20A02, Scer\GAL4DBD.R94B10

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R25D01, Hsap\RELAAD.R52G04, Scer\GAL4DBD.R19F09, Scer\GAL4DBD.R94B10

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R25D01, Hsap\RELAAD.R71D08, Scer\GAL4DBD.R11F03, Scer\GAL4DBD.R19F09

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R25D01, Hsap\RELAAD.R93D10, Scer\GAL4DBD.R13F04, Scer\GAL4DBD.R19F09

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R25D01, Scer\GAL4DBD.R19F09

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R30E08, Scer\GAL4DBD.R53C10

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R47H03, Scer\GAL4DBD.R72E01

      (von Reyn et al., 2017)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R47H03, Scer\GAL4DBD.R86D05

      (von Reyn et al., 2017)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R49C04, Scer\GAL4DBD.R72E01

      (von Reyn et al., 2017)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R52G04, Hsap\RELAAD.R93D10, Scer\GAL4DBD.R13F04, Scer\GAL4DBD.R94B10

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R52G04, Scer\GAL4DBD.R94B10

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R53C03, Scer\GAL4DBD.R24E12

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R64B03, Scer\GAL4DBD.R29G08

      (Cande et al., 2018)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R71D08, Scer\GAL4DBD.R11F03

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R73H08, Scer\GAL4DBD.R19F09

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.R93D10, Scer\GAL4DBD.R13F04

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.VT023490, Scer\GAL4DBD.R38F04

      (Cande et al., 2018)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.VT040012, Scer\GAL4DBD.VT043656

      (Ribeiro et al., 2018)

      abnormal locomotor behavior | adult stage | conditional, with Hsap\RELAAD.VT049749, Scer\GAL4DBD.VT013121

      (Cande et al., 2018)

      abnormal locomotor behavior | adult stage | conditional, with Scer\GAL40273-G4

      (Stern et al., 2019)

      abnormal locomotor behavior | adult stage | conditional, with Scer\GAL40273-G4, Scer\GAL4GMR58E02

      (Stern et al., 2019)

      abnormal locomotor behavior | adult stage | conditional, with Scer\GAL40273-G4, Scer\GAL4Gr66a.PD

      (Stern et al., 2019)

      abnormal locomotor behavior | adult stage | conditional, with Scer\GAL40273-G4, Scer\GAL80ple.PK

      (Stern et al., 2019)

      abnormal locomotor behavior | adult stage | conditional, with Scer\GAL4Foma1

      (von Reyn et al., 2017)

      abnormal locomotor behavior | adult stage | conditional, with Scer\GAL4GMR23E10

      (Troup et al., 2018)

      abnormal locomotor behavior | adult stage | conditional, with Scer\GAL4Gr63a.PD

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Scer\GAL4Gr66a.PD

      (Shao et al., 2017, Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Scer\GAL4Ir76b.916

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Scer\GAL4NP0225

      (Aso et al., 2014)

      abnormal locomotor behavior | adult stage | conditional, with Scer\GAL4NPF.1

      (Shao et al., 2017)

      abnormal locomotor behavior | larval stage, with Scer\GAL4EL.eveRC

      (Marshall and Heckscher, 2022)

      abnormal locomotor behavior | larval stage | conditional, with Hsap\RELAAD.eve.EL, Scer\GAL4DBD.R11F02

      (Heckscher et al., 2015)

      abnormal locomotor behavior | larval stage | conditional, with Hsap\RELAAD.R15F02, Scer\GAL4DBD.R15B07

      (Hasegawa et al., 2016)

      abnormal locomotor behavior | larval stage | conditional, with Hsap\RELAAD.R15F02, Scer\GAL4DBD.R47E12

      (Hasegawa et al., 2016)

      abnormal locomotor behavior | larval stage | conditional, with Hsap\RELAAD.R23E07, Scer\GAL4DBD.VT002081

      (Tastekin et al., 2018)

      abnormal locomotor behavior | larval stage | conditional, with Hsap\RELAAD.R57F07, Scer\GAL4DBD.R15B07

      (Hasegawa et al., 2016)

      abnormal locomotor behavior | larval stage | conditional, with Hsap\RELAAD.R82E12, Scer\GAL4DBD.Rab11.6.14.3

      (Hu et al., 2017)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL419-12, Scer\GAL80tsh-md621-GAL80

      (Hu et al., 2017)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL41003.3, Scer\GAL80tsh-md621-GAL80

      (Hu et al., 2017)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL4EL.eveRC

      (Heckscher et al., 2015)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL4GMR47E12, Scer\GAL80ChAT.3.3P

      (Hasegawa et al., 2016)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL4GMR47E12, Scer\GAL80ChAT.3.3P, Scer\GAL80tsh-md621-GAL80

      (Hasegawa et al., 2016)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL4GMR57B04

      (van Giesen et al., 2016)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL4GMR75C02

      (Tastekin et al., 2018)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL4GMR78A01, Scer\GAL80ppk.1.0

      (Hu et al., 2017)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL4GMR82E12

      (Hu et al., 2017)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL4Gr10a.3.7

      (van Giesen et al., 2016)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL4Gr21a.PU

      (van Giesen et al., 2016)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL4ppk.PG

      (Hu et al., 2017)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL4Rab11.6.14.3

      (Hu et al., 2017)

      abnormal locomotor behavior | larval stage | conditional, with Scer\GAL4VT025803

      (Takagi et al., 2017)

      abnormal mating | male limited | conditional, with Scer\GAL4Crz.391

      (Zer-Krispil et al., 2018)

      abnormal mating | male limited | conditional, with Scer\GAL4CrzR.3.5

      (Zer-Krispil et al., 2018)

      abnormal mating behavior | female, with Scer\GAL4Ir52a.PK

      (He et al., 2019)

      abnormal memory | adult stage | conditional, with Hsap\RELAAD.R58E02, Scer\GAL4DBD.R32D11

      (Takemura et al., 2017)

      abnormal memory | adult stage | conditional, with Hsap\RELAAD.VT026773, Scer\GAL4DBD.R72B05

      (Takemura et al., 2017)

      abnormal memory | adult stage | conditional, with Scer\GAL4Crz.391

      (Zer-Krispil et al., 2018)

      abnormal memory | adult stage | conditional, with Scer\GAL4Gr66a.PD

      (Shao et al., 2017)

      abnormal memory | adult stage | conditional, with Scer\GAL4NPF.1

      (Shao et al., 2017)

      abnormal memory | larval stage, with Scer\GAL4GMR58E02

      (Eichler et al., 2017)

      abnormal memory | larval stage | conditional, with Hsap\RELAAD.R13D05, Scer\GAL4DBD.R36B06

      (Saumweber et al., 2018)

      abnormal neuroanatomy | larval stage, with Scer\GAL4ppk.PG

      (Hu et al., 2017)

      abnormal neurophysiology | adult stage | conditional, with Hsap\RELAAD.R13F02, Scer\GAL4DBD.R44E04

      (Takemura et al., 2017)

      abnormal neurophysiology | adult stage | conditional, with Hsap\RELAAD.R19G02, Scer\GAL4DBD.R75G12

      (Klapoetke et al., 2017)

      abnormal neurophysiology | adult stage | conditional, with Hsap\RELAAD.R47H03, Scer\GAL4DBD.R72E01

      (von Reyn et al., 2017)

      abnormal neurophysiology | adult stage | conditional, with Hsap\RELAAD.R58E02, Scer\GAL4DBD.R32D11

      (Takemura et al., 2017)

      abnormal neurophysiology | adult stage | conditional, with Scer\GAL4GMR23E10

      (Troup et al., 2018)

      abnormal neurophysiology | adult stage | conditional, with Scer\GAL4GMR24C06

      (Suver et al., 2019)

      abnormal neurophysiology | adult stage | conditional, with Scer\GAL4GMR45D07

      (Suver et al., 2019)

      abnormal neurophysiology | cell non-autonomous | conditional, with Scer\GAL4nompC.PC

      (Zhou et al., 2019)

      abnormal neurophysiology | larval stage | conditional, with Scer\GAL4VGlut-OK371

      (Klapoetke et al., 2014)

      abnormal oviposition | conditional, with Scer\GAL4Tmc.3.0, Scer\GAL80VGlut.PV

      (Wu et al., 2019)

      abnormal pain response | larval stage | conditional

      (Luo et al., 2017)

      abnormal pain response | larval stage | conditional, with Scer\GAL4Ilp7.PY

      (Hu et al., 2017)

      abnormal phototaxis | adult stage | conditional, with Scer\GAL4CrzR.3.5

      (Zer-Krispil et al., 2018)

      abnormal phototaxis | adult stage | male limited | conditional, with Scer\GAL4Crz.391

      (Zer-Krispil et al., 2018)

      abnormal proboscis extension reflex | adult stage | conditional, with Scer\GAL4Gr28b.b.4.7

      (Zhan et al., 2016)

      abnormal proboscis extension reflex | adult stage | conditional, with Scer\GAL4Gr64f.9.7

      (Klapoetke et al., 2014)

      abnormal proboscis extension reflex | conditional, with Scer\GAL4C220

      (Kim et al., 2017)

      abnormal proboscis extension reflex | conditional, with Scer\GAL4GMR11H09

      (Kim et al., 2017)

      abnormal proboscis extension reflex | conditional, with Scer\GAL4GMR30A08

      (Kim et al., 2017)

      abnormal proboscis extension reflex | conditional, with Scer\GAL4Gr64f.9.7

      (Kim et al., 2017)

      abnormal proboscis extension reflex | conditional, with Scer\GAL4Gr66a.3.153

      (Kim et al., 2017)

      abnormal proboscis extension reflex | conditional, with Scer\GAL4VT057358

      (Kim et al., 2017)

      abnormal proboscis extension reflex | light conditional, with Ecol\lexAGr66a.PS, Scer\GAL4alka.PM, Scer\GAL80IVS.WPRE.8xlexAop

      (Mi et al., 2023)

      abnormal proboscis extension reflex | light conditional, with Scer\GAL4alka.PM

      (Mi et al., 2023)

      abnormal proboscis extension reflex | light conditional, with Scer\GAL4alka.PM, Scer\GAL80Orco.5058

      (Mi et al., 2023)

      abnormal proboscis extension reflex | light conditional, with Scer\GAL4Gr66a.PD

      (Sang et al., 2024)

      abnormal proboscis extension reflex | light conditional, with Scer\GAL4Ir60b.PK

      (Sang et al., 2024)

      abnormal size | adult stage | conditional, with Scer\GAL4Gr28b.b.4.7

      (Zhan et al., 2016)

      abnormal sleep | adult stage | conditional, with Scer\GAL43A

      (Kirszenblat et al., 2019)

      abnormal sleep | adult stage | conditional, with Scer\GAL4GMR23E10

      (Troup et al., 2018)

      abnormal sleep | adult stage | conditional, with Scer\GAL4GMR27B03

      (Kirszenblat et al., 2019)

      abnormal sleep | adult stage | conditional, with Scer\GAL4GMR37G12

      (Xie et al., 2019)

      abnormal sleep | adult stage | conditional, with Scer\GAL4GMR79D04

      (Kirszenblat et al., 2019)

      abnormal sleep | adult stage | conditional, with Scer\GAL4GMR.PU

      (Kirszenblat et al., 2019)

      abnormal song | conditional, with Scer\FLP1FLPo.oc.Tag:NLS(SV40-largeT), Scer\GAL4Tdc2.PC, Scer\GAL80FRT.αTub84B

      (O'Sullivan et al., 2018)

      abnormal song | conditional, with Scer\GAL4Tdc2.PC

      (O'Sullivan et al., 2018)

      abnormal song | conditional, with Scer\GAL4Tdc2.PC, Scer\GAL80tsh-md621-GAL80

      (O'Sullivan et al., 2018)

      decreased rate of movement | adult stage | conditional, with Scer\GAL4NPF.1

      (Shao et al., 2017)

      increased rate of movement | adult stage | conditional, with Hsap\RELAAD.VT017683, Scer\GAL4DBD.VT031084

      (Cande et al., 2018)

      increased rate of movement | adult stage | conditional, with Hsap\RELAAD.VT040232, Scer\GAL4DBD.VT029310

      (O'Sullivan et al., 2018)

      increased rate of movement | adult stage | conditional, with Hsap\RELAAD.VT040232, Scer\GAL4DBD.VT042475

      (O'Sullivan et al., 2018)

      increased rate of movement | adult stage | conditional, with Hsap\RELAAD.VT045969, Scer\GAL4DBD.VT042475

      (O'Sullivan et al., 2018)

      increased rate of movement | larval stage | conditional, with Hsap\RELAAD.R23E07, Scer\GAL4DBD.VT002081

      (Tastekin et al., 2018)

      increased rate of movement | larval stage | conditional, with Hsap\RELAAD.R26D04, Scer\GAL4DBD.R48H02

      (Takagi et al., 2017)

      increased rate of movement | larval stage | conditional, with Scer\GAL4GMR23F01

      (Tastekin et al., 2015)

      increased rate of movement | larval stage | conditional, with Scer\GAL4GMR23F01, Scer\GAL80tsh-md621-GAL80

      (Tastekin et al., 2015)

      increased rate of movement | larval stage | conditional, with Scer\GAL4GMR75C02

      (Tastekin et al., 2018)

      increased rate of movement | larval stage | conditional, with Scer\GAL4GMR82B10

      (Zhao et al., 2019)

      increased rate of movement | larval stage | conditional, with Scer\GAL4NP4820

      (Tastekin et al., 2015)

      paralytic | adult stage | conditional, with Scer\GAL4Gr28b.b.4.7

      (Zhan et al., 2016)

      uncoordinated | larval stage | conditional, with Hsap\RELAAD.R21F05, Scer\GAL4DBD.R58E05

      (Zwart et al., 2016)

      uncoordinated | larval stage | conditional, with Hsap\RELAAD.R32C05, Scer\GAL4DBD.R38E10

      (Zwart et al., 2016)

      uncoordinated | larval stage | conditional, with Hsap\RELAAD.VT059793, Scer\GAL4DBD.R58F03

      (Zwart et al., 2016)

      uncoordinated | larval stage | conditional, with Scer\GAL4GMR83H09

      (Zwart et al., 2016)
      Phenotype Manifest In

      adult fat body | conditional, with Scer\GAL4Gr28b.b.4.7

      (Zhan et al., 2016)

      adult motor neuron | cell non-autonomous | conditional, with Scer\GAL4nompC.PC

      (Zhou et al., 2019)

      embryonic/larval hypodermal muscle cell | conditional, with Hsap\RELAAD.R26D04, Scer\GAL4DBD.R48H02

      (Takagi et al., 2017)

      embryonic/larval hypodermal muscle cell | conditional, with Scer\GAL4GMR47E12, Scer\GAL80ChAT.3.3P

      (Hasegawa et al., 2016)

      embryonic/larval hypodermal muscle cell | conditional, with Scer\GAL4VT025803

      (Takagi et al., 2017)

      fan-shaped body | conditional, with Scer\GAL4GMR23E10

      (Troup et al., 2018)

      giant fiber neuron | conditional, with Hsap\RELAAD.R19G02, Scer\GAL4DBD.R75G12

      (Klapoetke et al., 2017)

      giant fiber neuron | conditional, with Hsap\RELAAD.R47H03, Scer\GAL4DBD.R72E01

      (von Reyn et al., 2017)

      labellum | conditional, with Scer\GAL4GMR18B07

      (Zhou et al., 2019)

      larval abdomen | conditional, with Hsap\RELAAD.R15F02, Scer\GAL4DBD.R15B07

      (Hasegawa et al., 2016)

      larval abdomen | conditional, with Hsap\RELAAD.R15F02, Scer\GAL4DBD.R47E12

      (Hasegawa et al., 2016)

      larval abdomen | conditional, with Hsap\RELAAD.R57F07, Scer\GAL4DBD.R15B07

      (Hasegawa et al., 2016)

      larval abdomen | conditional, with Scer\GAL4GMR47E12, Scer\GAL80ChAT.3.3P

      (Hasegawa et al., 2016)

      larval abdomen | conditional, with Scer\GAL4GMR47E12, Scer\GAL80ChAT.3.3P, Scer\GAL80tsh-md621-GAL80

      (Hasegawa et al., 2016)

      larval head | conditional, with Hsap\RELAAD.R23E07, Scer\GAL4DBD.VT002081

      (Tastekin et al., 2018)

      larval head | conditional, with Scer\GAL4GMR23F01

      (Tastekin et al., 2015)

      larval head | conditional, with Scer\GAL4GMR23F01, Scer\GAL80tsh-md621-GAL80

      (Tastekin et al., 2015)

      larval head | conditional, with Scer\GAL4GMR75C02

      (Tastekin et al., 2018)

      larval head | conditional, with Scer\GAL4GMR82B10

      (Zhao et al., 2019)

      larval head | conditional, with Scer\GAL4NP4820

      (Tastekin et al., 2015)

      larval multidendritic class IV neuron | larval stage, with Scer\GAL4ppk.PG

      (Hu et al., 2017)

      muscle cell of lateral transverse muscle 2 | conditional, with Hsap\RELAAD.R21F05, Scer\GAL4DBD.R58E05

      (Zwart et al., 2016)

      muscle cell of lateral transverse muscle 2 | conditional, with Hsap\RELAAD.R32C05, Scer\GAL4DBD.R38E10

      (Zwart et al., 2016)

      muscle cell of lateral transverse muscle 2 | conditional, with Hsap\RELAAD.VT059793, Scer\GAL4DBD.R58F03

      (Zwart et al., 2016)

      muscle cell of lateral transverse muscle 2 | conditional, with Scer\GAL4GMR83H09

      (Zwart et al., 2016)

      mushroom body output neuron 7 | conditional, with Hsap\RELAAD.R13F02, Scer\GAL4DBD.R44E04

      (Takemura et al., 2017)

      mushroom body output neuron 7 | conditional, with Hsap\RELAAD.R58E02, Scer\GAL4DBD.R32D11

      (Takemura et al., 2017)

      wedge projection neuron | conditional, with Scer\GAL4GMR24C06

      (Suver et al., 2019)

      wedge projection neuron | conditional, with Scer\GAL4GMR45D07

      (Suver et al., 2019)

      wing | adult stage | conditional, with Hsap\RELAAD.VT017683, Scer\GAL4DBD.VT031084

      (Cande et al., 2018)

      wing | conditional, with Hsap\RELAAD.VT040232, Scer\GAL4DBD.VT029310

      (O'Sullivan et al., 2018)

      wing | conditional, with Hsap\RELAAD.VT040232, Scer\GAL4DBD.VT042475

      (O'Sullivan et al., 2018)

      wing | conditional, with Hsap\RELAAD.VT045969, Scer\GAL4DBD.VT042475

      (O'Sullivan et al., 2018)
      Detailed Description
      Statement
      Reference

      In larvae expressing Zzzz\ChR1IVS.20xScer\UAS.T:Avic\GFP-YFP.Venus in motor neurons (via Scer\GAL4VGlut-OK371), both 470-nm and 617-nm light triggers EJPs, even at short (1- to 2-ms) light-pulse durations and low intensities. In response to light-pulse durations over 2 ms, Zzzz\ChR1IVS.20xScer\UAS.T:Avic\GFP-YFP.Venus expression triggers long-lasting barrages of EJPs. Long-wavelength red light (720 nm) also triggers EJPs, though high-intensity light and long light-pulse durations (40–160 ms) are required for robust activation of the NMJ.

      In adults expressing Zzzz\ChR1IVS.20xScer\UAS.T:Avic\GFP-YFP.Venus in sweet taste receptor cells (via Scer\GAL4Gr64f.9.7), proboscis extension reflexes are robustly elicited at very low 470 nm and 617 nm light intensities. Flies also respond to 720-nm light at an intensity substantially lower than that required in the larvae.

      Adults expressing Zzzz\ChR1IVS.20xScer\UAS.T:Avic\GFP-YFP.Venus in PNv-1 antennal lobe neurons that innervate the V glomerulus (via Scer\GAL4VT31497) which induces an avoidance response to CO[[2]], reliably avoid quadrants in a circular arena lit by weak red light (617 nm).

      (Klapoetke et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhanced by
      Suppressed by
      Statement
      Reference

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL4EL.eveRC has abnormal locomotor behavior | larval stage phenotype, suppressible by Df(2R)eve/Df(2R)eve/eveΔEL/eveΔEL

      (Marshall and Heckscher, 2022)

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL40273-G4 has abnormal locomotor behavior | adult stage | conditional phenotype, suppressible | conditional | partially by norpAP24

      (Stern et al., 2019)

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL40273-G4 has abnormal locomotor behavior | adult stage | conditional phenotype, suppressible | partially by Dop1R1f02676

      (Stern et al., 2019)

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL40273-G4 has abnormal locomotor behavior | adult stage | conditional phenotype, suppressible | partially by Dop2Rf06521

      (Stern et al., 2019)

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL40273-G4 has abnormal locomotor behavior | adult stage | conditional phenotype, suppressible | partially by pleHMC06137, Scer\GAL40273-G4

      (Stern et al., 2019)

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL40273-G4 has abnormal locomotor behavior | adult stage | conditional phenotype, suppressible | conditional | partially by Gthe\ACR1lexAop.d.EYFP/Ecol\lexAGMR13F02

      (Stern et al., 2019)

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL40273-G4, norpAP24 has abnormal locomotor behavior | adult stage | conditional phenotype, suppressible | conditional | partially by Gthe\ACR1lexAop.d.EYFP/Ecol\lexAGMR13F02

      (Stern et al., 2019)

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL40273-G4, norpAP24 has abnormal locomotor behavior | adult stage | conditional phenotype, suppressible | conditional | partially by Gthe\ACR1lexAop.d.EYFP/Ecol\lexAVP16.Mef2.247

      (Stern et al., 2019)

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL40273-G4 has abnormal locomotor behavior | adult stage | conditional phenotype, suppressible | conditional | partially by Gthe\ACR1lexAop.d.EYFP/Ecol\lexAGMR38G08

      (Stern et al., 2019)

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Hsap\RELAAD.R23E07, Scer\GAL4DBD.VT002081 has abnormal locomotor behavior | larval stage | conditional phenotype, suppressible by VAChTGD3054, Hsap\RELAAD.R23E07, Scer\GAL4DBD.VT002081

      (Tastekin et al., 2018)

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL4GMR23E10 has abnormal locomotor behavior | adult stage | conditional phenotype, suppressible | partially by Inx6GD3692, Scer\GAL4GMR23E10

      (Troup et al., 2018)

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL4GMR23E10 has abnormal neurophysiology | adult stage | conditional phenotype, suppressible | partially by Inx6GD3692, Scer\GAL4GMR23E10

      (Troup et al., 2018)

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL4GMR23E10 has abnormal sleep | adult stage | conditional phenotype, suppressible | partially by Inx6GD3692, Scer\GAL4GMR23E10

      (Troup et al., 2018)

      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL4NPF.1 has abnormal locomotor behavior | adult stage | conditional phenotype, suppressible | partially by NPFRNAi.UAS, Scer\GAL4NPF.1

      (Shao et al., 2017)
      NOT suppressed by
      Suppressor of
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (14)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus
      Cnoc\ChR1Cs.IVS.20xScer\UAS.T:Avic\GFP-YFP.Venus
      Cnoc\ChR1Cs.IVS.20xUAS.Venus
      Zzzz\ChR1Cs.IVS.20xScer\UAS.T:Avic\GFP-YFP.Venus
      Zzzz\ChR1IVS.20xScer\UAS.T:Avic\GFP-YFP.Venus
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0321310
      • FBal0320696
      • FBal0295146
      • FBal0351218
      References (239)