Sam50
Please see the JBrowse view of Dmel\qkr54B for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Stop-codon suppression (UGA) postulated (FBrf0219254, FlyBase analysis, supported by preponderance of gene model predictions.
Gene model reviewed during 5.44
Gene model reviewed during 5.48
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
4.6, 4.0, 2.8, 2.5 (northern blot)
428 (aa)
A Myc-epitope-tagged qkr54B protein expressed in HeLa cells migrates with a molecular mass of approximately 50 kD. qkr54B protein binds homopolymeric RNA in vitro (poly(A) and poly(U)), and the GSG domain is necessary but not sufficient for RNA binding. qkr54B protein can associate into homomultimers, and the GSG domain is necessary for this self-association. A GFPFBtr0091350:pb-XRqkr54B fusion protein activates apoptotic pathways in mouse NIH 3T3 and Drosophila S2 cells.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\qkr54B using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
Comment: reference states 0-4 hr AEL
JBrowse - Visual display of RNA-Seq signals
View Dmel\qkr54B in JBrowse2-82
2-86.2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: qkr54B Sam50
Source for merge of qkr54B Sam50 was sequence comparison ( date:000114 ).