dnab, l(3)64Aj
transcriptional cofactor - co-activator of Squeeze in CNS neurons - co-repressor of Rotund in wing - interacts with Brinker to eliminate cells with reduced Dpp signaling
Please see the JBrowse view of Dmel\nab for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.45
Alternative translation stop created by use of multiphasic reading frames within coding region.
None of the polypeptides share 100% sequence identity.
Interacts with sqz and rn. Able to bind mammalian EGR1 but not Drosophila EGR-like protein klu.
The NAB conserved domain 2 (NCD2) is necessary for transcriptional repression.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\nab using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
nab is expressed just before the thoracic neuroblast 3-3 produces its last GMC that gives rise to the sixth-born EL neuron.
A low level of nab expression is seen in all imaginal discs. In late third instar wing discs, nab was strongly expressed in a circular domain that delimits the expression of wg in the IR. A low level of expression is seen in the rest of the wing disc, except in the hinge region. nab expression is detected in a stripe corresponding to the morphogenetic furrow in the eye disc.
JBrowse - Visual display of RNA-Seq signals
View Dmel\nab in JBrowse3-10
3-8.9
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Annotations CG15000 and CG15001 merged as CG33545 (which corresponds to nab) in release 4.1 of the genome annotation.
1 allele of l(3)SH143 recovered in a P-insertion screen.
Source for merge of: l(3)SH143 nab
Source for merge of: CG15000 CG15001
Source for identity of: nab l(3)64Aj
Source for identity of: nab CG15000 CG15001