jnj, HU- or caffeine-sensitive 95E, java no jive, huc95E
Please see the JBrowse view of Dmel\SMC6 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\SMC6 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\SMC6 in JBrowse3-84
3-82.8
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Identification: isolated as a conditional eye mutant, in clones, that is sensitive to hydroxyurea and caffeine.
Eye development is severely disrupted in response to the presence of caffeine, but not hydroxyurea, and third instar eye discs are extremely fragile. Hemizygotes for this mutant grown in the absence of caffeine are viable and fertile, but in the presence of caffeine fail to complete pupal development.
Source for merge of: SMC6 CG5524
Source for identity of: huc95E Huc-95DE
Source for identity of: SMC6 huc95E