Acon, Aconitase, mitochondrial aconitase, ACON-1, m-aconitase
Please see the JBrowse view of Dmel\mAcon1 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.52
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.56
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mAcon1 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
JBrowse - Visual display of RNA-Seq signals
View Dmel\mAcon1 in JBrowse2-54
2-54.5
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
ChEST reveals this is a target of Mef2.
Mutants isolated in a screen of the second chromosome identifying genes affecting disc morphology.
No difference in allele fixed in lines selected over 700 generations for high (negative) and low (positive) geotaxis.
Source for merge of: Acon l(2)07054
Source for merge of: Acon BEST:GH10550
Source for merge of: Acon CG9244
Source for merge of Acon CG9244 was sequence comparison ( date:000608 ).
Source for identity of: mAcon1 Acon
Renamed from 'Acon' (Aconitase) to 'mAcon1' (Mitochondrial aconitase 1) to reflect that this is a mitochondrial, rather than cytoplasmic, aconitase. This is consistent with the nomenclature used for this gene/protein from several publications. Added a '1' suffix to distinguish it from the other, less studied mitochondrial aconitase (CG4706/mAcon2) that is mainly expressed in the testis (see FBrf0221188).