FlyBase Allele Report: Dmel\E2f1[UAS.cNa]

Adulthood-only expression of E2f1^UAS.cNa under the control of Scer\GAL4^esg.PU leads to an increase in the number of intestinal progenitors (esg-positive ISCs and EBs) and an increase in mitotic index in the adult posterior midgut epithelium.

(Zhao et al., 2022)

Expressing E2f1^UAS.cNa under the control of Scer\GAL4^GMR.long does not have a major effect on retinal morphology, as compared to controls.

(Bervoets et al., 2019)

The expression of E2f1^UAS.cNa for 3 days during larval development under the combined control of Scer\GAL4^ap-md544 and Gal80[ts] induces an increased DNA damage response (phospho-H2Av) in third instar larval wing discs.

(Murcia et al., 2019)

Expression of E2f^Scer\UAS.cNa under the control of Scer\GAL4^Act88F.PD results in wings which are gnarled, downward-curved and/or blistered.

(Truscott et al., 2011)

Scer\GAL4^Act88F.PD, E2f^Scer\UAS.cNa flies display multiple wing defects.

(Moon et al., 2008)

Expression of E2f^Scer\UAS.cNa under the control of Scer\GAL4^Act88F.PD results in an gnarled wing phenotype.

(Morris et al., 2008)

Scer\GAL4^Act88F.PD-driven expression of E2f^Scer\UAS.cNa causes punctate pattern of cell cell death in the distal wing blade of newly eclosed adults.

Scer\GAL4^GMR.PF driven expression of E2f^Scer\UAS.cNa causes a blackened and rough eye phenotype.

(Morris et al., 2006)

Ectopic expression of E2f^Scer\UAS.cNa under the regulation of Scer\GAL4^sca-537.4 results in an increase in cell number in some abdominal hemisegments. In addition transformation of NB6-4a to NB6-4t is observed at low penetrance (13%).

(Berger et al., 2005)

The average cell doubling time in wing disc cells expressing E2f^Scer\UAS.cNa under the control of Scer\GAL4^Act5C.PP is shortened to 9.5 hours (compared to 12 hours for wild-type cells). The average duration of cell cycle phases in these cells is: G1 = 1.4 hours, S = 4.6 hours and G2 = 3.5 hours (wild-type values are G1 = 3.4 hours, S = 4.4 hours and G2 = 4.2 hours). The number of posterior cells in wing discs expressing E2f^Scer\UAS.cNa under the control of Scer\GAL4^en-e16E is higher than that of wild-type discs.

(Neufeld et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^esg.PU has increased cell growth rate | adult stage | male phenotype, enhanceable by shd^HMC06461, Scer\GAL4^esg.PU

(Sekar et al., 2023)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.long has visible | adult stage phenotype, enhanceable by Hsap\YARS1^E196K.UAS, Scer\GAL4^GMR.long

(Bervoets et al., 2019)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, enhanceable by Asx[+]/Asx¹

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, enhanceable by pho[+]/pho¹

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, enhanceable by Su(z)2^1.b7/Su(z)2[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, enhanceable by Su(z)2^k06344/Su(z)2[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, enhanceable by tou²/tou[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by His2Av[+]/His2Av⁸¹⁰

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by His2Av[+]/His2Av⁰⁵¹⁴⁶

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Pc³/Pc[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Pc[+]/Pc^f01890

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Su(z)2¹/Su(z)2[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, enhanceable by sgg^UAS.cBa, Scer\GAL4^Act88F.PD

(Morris et al., 2008)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, enhanceable by Dp^UAS.cDa, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, enhanceable by Diap1^j5C8

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, enhanceable by cass^k06710

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^nanos.PG has visible phenotype, enhanceable by cass^k06710

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by cass^k06710

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by cass^RNAi.UAS, Scer\GAL4^GMR.PF

(Morris et al., 2006)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^ptc-559.1 has increased occurrence of cell division | larval stage phenotype, enhanceable by mir-ban^EP3622

(Brennecke et al., 2003)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^ptc-559.1 has decreased cell death | larval stage phenotype, enhanceable by mir-ban^EP3622

(Brennecke et al., 2003)

E2f1^UAS.cNa, Scer\GAL4^Act5C.PP has abnormal mitotic cell cycle phenotype, enhanceable by Dp^UAS.cDa, Scer\GAL4^Act5C.PP

(Neufeld et al., 1998)

NOT Enhanced by

Statement

Reference

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.long has visible | adult stage phenotype, non-enhanceable by Hsap\YARS1^WT.UAS, Scer\GAL4^GMR.long

(Bervoets et al., 2019)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-enhanceable by eff[+]/eff^mer4

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-enhanceable by e(Pc)84DE^T66.1/e(Pc)84DE[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-enhanceable by kis^BG01657/kis[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-enhanceable by Su(z)2^1.a1/Su(z)2[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-enhanceable by Su(z)12³/Su(z)12[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-enhanceable by brm[+]/brm²

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-enhanceable by trx[+]/trx^KG08639

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by Asx[+]/Asx¹

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by eff[+]/eff^mer4

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by e(Pc)84DE^T66.1/e(Pc)84DE[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by kis^BG01657/kis[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by pho[+]/pho¹

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by Su(z)2^1.a1/Su(z)2[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by Su(z)2^1.b7/Su(z)2[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by Su(z)2^k06344/Su(z)2[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by Su(z)12³/Su(z)12[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by tara¹/tara[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by tou²/tou[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by brm[+]/brm²

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by trx[+]/trx^KG08639

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by Mi-2[+]/Mi-2^j3D4

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has increased cell death phenotype, non-enhanceable by p53^5A-1-4

(Moon et al., 2008)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-enhanceable by p53^259H.GUS, Scer\GAL4^Act88F.PD

(Moon et al., 2008)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by p53^259H.GUS, Scer\GAL4^GMR.PF

(Moon et al., 2008)

Suppressed by

Statement

Reference

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^esg.PU has abnormal cell cycle | male | adult stage phenotype, suppressible by EcR^JF02538, Scer\GAL4^esg.PU

(Sekar et al., 2023)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^esg.PU has increased cell growth rate | male | adult stage phenotype, suppressible by E2f1^JF02718, Scer\GAL4^esg.PU

(Sekar et al., 2023)

E2f1^UAS.cNa has increased cell death phenotype, suppressible by mir-11^UAS.DsRed2/Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Truscott et al., 2014)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has increased cell death phenotype, suppressible by mir-11^UAS.DsRed2, Scer\GAL4^GMR.PU

(Truscott et al., 2014)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, suppressible | partially by Mi-2[+]/Mi-2^j3D4

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, suppressible | partially by Su(z)2[+]/Su(z)2^3-1

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, suppressible | partially by E(Pc)[+]/E(Pc)^w3

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, suppressible | partially by E(Pc)^D4/E(Pc)[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has increased cell death phenotype, suppressible by mir-11^UAS.DsRed2, Scer\GAL4^GMR.PF

(Truscott et al., 2011)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has increased cell death phenotype, suppressible by BacA\p35^UAS.cUa, Scer\GAL4^GMR.PF

(Truscott et al., 2011)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, suppressible by mir-11^UAS.DsRed2, Scer\GAL4^Act88F.PD

(Truscott et al., 2011)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, suppressible by Rbf^UAS.cDa, Scer\GAL4^Act88F.PD

(Moon et al., 2008, Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, suppressible by pan^UAS.cWa, Scer\GAL4^Act88F.PD

(Morris et al., 2008)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, suppressible | partially by arm^{S2.UAS.Tag:MYC}, Scer\GAL4^Act88F.PD

(Morris et al., 2008)

BacA\p35^UAS.cHa, Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^vg.int2.1 has visible phenotype, suppressible | partially by vg[+]/vg^null

(Legent et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, suppressible by Dp^DN.UAS.cMa, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, suppressible by Dark^CD4/Ark[+]

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

NOT suppressed by

Statement

Reference

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^esg.PU has abnormal cell cycle | male | adult stage phenotype, non-suppressible by Dad^UAS.cTa, Scer\GAL4^esg.PU

(Sekar et al., 2023)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^esg.PU has increased cell growth rate | male | adult stage phenotype, non-suppressible by Dad^UAS.cTa, Scer\GAL4^esg.PU

(Sekar et al., 2023)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^esg.PU has abnormal cell cycle | male | adult stage phenotype, non-suppressible by shd^HMC06461, Scer\GAL4^esg.PU

(Sekar et al., 2023)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.long has visible | adult stage phenotype, non-suppressible by Hsap\YARS1^WT.UAS, Scer\GAL4^GMR.long

(Bervoets et al., 2019)

E2f1^UAS.cNa has increased cell death phenotype, non-suppressible by mir-998^UAS.cTa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Truscott et al., 2014)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has increased cell death phenotype, non-suppressible by mir-998^UAS.cTa, Scer\GAL4^GMR.PU

(Truscott et al., 2014)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by eff[+]/eff^mer4

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by e(Pc)84DE^T66.1/e(Pc)84DE[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by kis^BG01657/kis[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by Su(z)2^1.a1/Su(z)2[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by Su(z)12³/Su(z)12[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by brm[+]/brm²

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by trx[+]/trx^KG08639

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by Asx[+]/Asx¹

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by eff[+]/eff^mer4

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by e(Pc)84DE^T66.1/e(Pc)84DE[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by kis^BG01657/kis[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by pho[+]/pho¹

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by Su(z)2^1.a1/Su(z)2[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by Su(z)2^1.b7/Su(z)2[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by Su(z)2^k06344/Su(z)2[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by Su(z)12³/Su(z)12[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by tara¹/tara[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by tou²/tou[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by brm[+]/brm²

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by trx[+]/trx^KG08639

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by Mi-2[+]/Mi-2^j3D4

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has abnormal cell cycle phenotype, non-suppressible by mir-11^UAS.DsRed2, Scer\GAL4^GMR.PF

(Truscott et al., 2011)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^ptc-559.1 has increased cell death phenotype, non-suppressible by pico^{UAS.Tag:polyHis,Tag:MYC}, Scer\GAL4^ptc-559.1

(Lyulcheva et al., 2008)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by p53^259H.GUS, Scer\GAL4^Act88F.PD

(Moon et al., 2008)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by p53^259H.GUS, Scer\GAL4^GMR.PF

(Moon et al., 2008)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has increased cell death phenotype, non-suppressible by p53^5A-1-4

(Moon et al., 2008)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by Cdk1², Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by Cdk2^unspecified, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by Cdk4^unspecified, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by Hsap\CDKN1A^UAS.cHa, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by dap^UAS.cdNa, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by CycE^AR95, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has visible phenotype, non-suppressible by stg⁰¹²³⁵, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

Suppressor of

Statement

Reference

E2f1^UAS.cNa/Scer\GAL4^Act5C.PI is a suppressor | partially of decreased cell number | somatic clone | adult stage phenotype of Phb1²⁰

(Zhao et al., 2022)

E2f1^UAS.cNa, Scer\GAL4^esg.PU is a suppressor of decreased cell number | adult stage phenotype of Phb1^HMS00702, Scer\GAL4^esg.PU

(Zhao et al., 2022)

E2f1^UAS.cNa, Scer\GAL4^esg.PU is a suppressor of decreased occurrence of cell division | adult stage phenotype of Phb1^HMS00702, Scer\GAL4^esg.PU

(Zhao et al., 2022)

E2f1^UAS.cNa/Scer\GAL4^Act5C.PI is a suppressor | partially of decreased cell number | somatic clone | adult stage phenotype of Phb2^Δ

(Zhao et al., 2022)

E2f1^UAS.cNa, Scer\GAL4^esg.PU is a suppressor of decreased cell number | adult stage phenotype of Phb2^GD8538, Scer\GAL4^esg.PU

(Zhao et al., 2022)

E2f1^UAS.cNa, Scer\GAL4^esg.PU is a suppressor of decreased occurrence of cell division | adult stage phenotype of Phb2^GD8538, Scer\GAL4^esg.PU

(Zhao et al., 2022)

E2f1^UAS.cNa/Scer\GAL4^Act5C.PI is a suppressor of decreased cell number | somatic clone | adult stage phenotype of dind^Δ9

(Zhao et al., 2022)

E2f1^UAS.cNa, Scer\GAL4^esg.PU is a suppressor of decreased cell number | adult stage phenotype of Scer\GAL4^esg.PU, dind^{RNAi.UAS.RNAi}

(Zhao et al., 2022)

E2f1^UAS.cNa, Scer\GAL4^esg.PU is a suppressor of decreased occurrence of cell division | adult stage phenotype of Scer\GAL4^esg.PU, dind^{RNAi.UAS.RNAi}

(Zhao et al., 2022)

E2f1^UAS.cNa, Dp^UAS.cDa, Scer\GAL4^GMR.PU is a suppressor | partially of visible phenotype of arm^S44Y.GMR

(Morris et al., 2008)

E2f1^UAS.cNa, Dp^UAS.cDa, Scer\GAL4^vg.int2.1, BacA\p35^UAS.cHa is a suppressor of visible phenotype of vg^83b27

(Legent et al., 2006)

Scer\GAL4^ptc-559.1, E2f1^UAS.cNa, BacA\p35^UAS.cHa is a suppressor of decreased occurrence of cell division | larval stage phenotype of vg^null

(Delanoue et al., 2004)

NOT Suppressor of

Statement

Reference

E2f1^UAS.cNa, Dp^UAS.cDa, CycA^UAS.cWa, Scer\GAL4^GMR.PF is a non-suppressor of abnormal mitotic cell cycle | somatic clone phenotype of Delta^RevF10

(Baonza and Freeman, 2005)

Other

Statement

Reference

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^esg.PU has increased cell growth rate | male | adult stage phenotype

(Sekar et al., 2023)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^esg.PU has abnormal cell cycle | male | adult stage phenotype

(Sekar et al., 2023)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^NP1624 has increased occurrence of cell division | spermatogenesis phenotype

(Sainz de la Maza et al., 2022)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^en.PU has increased occurrence of cell division | third instar larval stage phenotype

(Zhang et al., 2021)

Dp^UAS.cDa, E2f1⁰⁷¹⁷², E2f1^UAS.cNa, Scer\GAL4^Tub.PU has increased cell number | somatic clone | third instar larval stage phenotype

(Zhang et al., 2021)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.long has visible | adult stage phenotype

(Bervoets et al., 2019)

Dp^UAS.cDa, E2f1^UAS.cNa, Hsap\YARS1^E196K.UAS, Scer\GAL4^GMR.long has abnormal size | adult stage phenotype

(Bervoets et al., 2019)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^Su(H).GBE has increased occurrence of cell division | adult stage phenotype

(Kohlmaier et al., 2015)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^{Delta-05151-G} has increased occurrence of cell division | adult stage phenotype

(Kohlmaier et al., 2015)

Cdk2^UAS.Tag:MYC, CycE^UAS.cLa, Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^{Delta-05151-G} has increased occurrence of cell division | adult stage phenotype

(Kohlmaier et al., 2015)

Cdk2^UAS.Tag:MYC, CycE^UAS.cLa, Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^Su(H).GBE has increased occurrence of cell division | adult stage phenotype

(Kohlmaier et al., 2015)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD, tara[+]/tara^BG01673 has lethal phenotype

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU, tara[+]/tara^BG01673 has lethal phenotype

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has increased cell death phenotype

(Truscott et al., 2011)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has increased occurrence of cell division phenotype

(Truscott et al., 2011)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^ptc-559.1 has increased cell death phenotype

(Lyulcheva et al., 2008)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^{elav.Switch.PO} has increased cell death phenotype

(Khurana et al., 2006)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^elav.PLu has lethal phenotype

(Khurana et al., 2006)

BacA\p35^UAS.cHa, Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^vg.int2.1 has visible phenotype

(Legent et al., 2006)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has increased occurrence of cell division | larval stage phenotype

(Baonza and Freeman, 2005)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^ptc-559.1 has decreased cell death | larval stage phenotype

(Brennecke et al., 2003)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^ptc-559.1 has increased occurrence of cell division | larval stage phenotype

(Brennecke et al., 2003)

Phenotype Manifest In

Enhanced by

Statement

Reference

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^esg.PU has male accessory gland secondary cell phenotype, enhanceable by shd^HMC06461, Scer\GAL4^esg.PU

(Sekar et al., 2023)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.long has eye phenotype, enhanceable by Hsap\YARS1^E196K.UAS, Scer\GAL4^GMR.long

(Bervoets et al., 2019)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, enhanceable by Asx[+]/Asx¹

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, enhanceable by pho[+]/pho¹

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, enhanceable by Su(z)2^1.b7/Su(z)2[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, enhanceable by Su(z)2^k06344/Su(z)2[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, enhanceable by tou²/tou[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by His2Av[+]/His2Av⁸¹⁰

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by His2Av[+]/His2Av⁰⁵¹⁴⁶

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Pc³/Pc[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Pc[+]/Pc^f01890

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Su(z)2¹/Su(z)2[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, enhanceable by sgg^UAS.cBa, Scer\GAL4^Act88F.PD

(Morris et al., 2008)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, enhanceable by Dp^UAS.cDa, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, enhanceable by Diap1^j5C8

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, enhanceable by cass^k06710

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^nanos.PG has macrochaeta phenotype, enhanceable by cass^k06710

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by cass^k06710

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by cass^RNAi.UAS, Scer\GAL4^GMR.PF

(Morris et al., 2006)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^ptc-559.1 has wing disc phenotype, enhanceable by mir-ban^EP3622, Scer\GAL4^ptc-559.1

(Brennecke et al., 2003)

E2f1^UAS.cNa, Scer\GAL4^en-e16E has wing disc phenotype, enhanceable by Dp^UAS.cDa, Scer\GAL4^en-e16E

(Neufeld et al., 1998)

NOT Enhanced by

Statement

Reference

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.long has eye phenotype, non-enhanceable by Hsap\YARS1^WT.UAS, Scer\GAL4^GMR.long

(Bervoets et al., 2019)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-enhanceable by eff[+]/eff^mer4

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-enhanceable by e(Pc)84DE^T66.1/e(Pc)84DE[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-enhanceable by kis^BG01657/kis[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-enhanceable by Su(z)2^1.a1/Su(z)2[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-enhanceable by Su(z)12³/Su(z)12[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-enhanceable by brm[+]/brm²

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-enhanceable by trx[+]/trx^KG08639

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by Asx[+]/Asx¹

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by eff[+]/eff^mer4

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by e(Pc)84DE^T66.1/e(Pc)84DE[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by kis^BG01657/kis[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by pho[+]/pho¹

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by Su(z)2^1.a1/Su(z)2[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by Su(z)2^1.b7/Su(z)2[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by Su(z)2^k06344/Su(z)2[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by Su(z)12³/Su(z)12[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by tara¹/tara[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by tou²/tou[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by brm[+]/brm²

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by trx[+]/trx^KG08639

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by Mi-2[+]/Mi-2^j3D4

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing pouch phenotype, non-enhanceable by p53^259H.GUS, Scer\GAL4^Act88F.PD

(Moon et al., 2008)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by p53^259H.GUS, Scer\GAL4^GMR.PF

(Moon et al., 2008)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has eye disc posterior to the morphogenetic furrow phenotype, non-enhanceable by p53^5A-1-4

(Moon et al., 2008)

Suppressed by

Statement

Reference

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^esg.PU has male accessory gland secondary cell phenotype, suppressible by EcR^JF02538, Scer\GAL4^esg.PU

(Sekar et al., 2023)

E2f1^UAS.cNa has wing phenotype, suppressible by mir-11^UAS.DsRed2/Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Truscott et al., 2014)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye disc phenotype, suppressible by mir-11^UAS.DsRed2, Scer\GAL4^GMR.PU

(Truscott et al., 2014)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, suppressible | partially by E(Pc)[+]/E(Pc)^w3

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, suppressible | partially by E(Pc)^D4/E(Pc)[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, suppressible | partially by Mi-2[+]/Mi-2^j3D4

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, suppressible | partially by Su(z)2[+]/Su(z)2^3-1

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has eye disc phenotype, suppressible by mir-11^UAS.DsRed2, Scer\GAL4^GMR.PF

(Truscott et al., 2011)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has eye disc phenotype, suppressible by BacA\p35^UAS.cUa, Scer\GAL4^GMR.PF

(Truscott et al., 2011)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, suppressible by mir-11^UAS.DsRed2, Scer\GAL4^Act88F.PD

(Truscott et al., 2011)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing pouch phenotype, suppressible by Rbf^UAS.cDa, Scer\GAL4^Act88F.PD

(Moon et al., 2008)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, suppressible | partially by pan^UAS.cWa, Scer\GAL4^Act88F.PD

(Morris et al., 2008)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, suppressible by arm^{S2.UAS.Tag:MYC}, Scer\GAL4^Act88F.PD

(Morris et al., 2008)

BacA\p35^UAS.cHa, Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^vg.int2.1 has wing phenotype, suppressible | partially by vg[+]/vg^null

(Legent et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, suppressible by Rbf^UAS.cDa, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, suppressible by Dp^DN.UAS.cMa, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, suppressible by Dark^CD4/Ark[+]

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

NOT suppressed by

Statement

Reference

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^esg.PU has male accessory gland secondary cell phenotype, non-suppressible by Dad^UAS.cTa, Scer\GAL4^esg.PU

(Sekar et al., 2023)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.long has eye phenotype, non-suppressible by Hsap\YARS1^WT.UAS, Scer\GAL4^GMR.long

(Bervoets et al., 2019)

E2f1^UAS.cNa has wing phenotype, non-suppressible by mir-998^UAS.cTa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Truscott et al., 2014)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye disc phenotype, non-suppressible by mir-998^UAS.cTa, Scer\GAL4^GMR.PU

(Truscott et al., 2014)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-suppressible by eff[+]/eff^mer4

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-suppressible by e(Pc)84DE^T66.1/e(Pc)84DE[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-suppressible by kis^BG01657/kis[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-suppressible by Su(z)2^1.a1/Su(z)2[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-suppressible by Su(z)12³/Su(z)12[+]

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-suppressible by brm[+]/brm²

(Ji et al., 2012)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing phenotype, non-suppressible by trx[+]/trx^KG08639

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by Asx[+]/Asx¹

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by eff[+]/eff^mer4

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by e(Pc)84DE^T66.1/e(Pc)84DE[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by kis^BG01657/kis[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by pho[+]/pho¹

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by Su(z)2^1.a1/Su(z)2[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by Su(z)2^1.b7/Su(z)2[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by Su(z)2^k06344/Su(z)2[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by Su(z)12³/Su(z)12[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by tara¹/tara[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by tou²/tou[+]

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by brm[+]/brm²

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by trx[+]/trx^KG08639

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by Mi-2[+]/Mi-2^j3D4

(Ji et al., 2012)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has eye disc phenotype, non-suppressible by mir-11^UAS.DsRed2, Scer\GAL4^GMR.PF

(Truscott et al., 2011)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^ptc-559.1 has wing disc phenotype, non-suppressible by pico^{UAS.Tag:polyHis,Tag:MYC}, Scer\GAL4^ptc-559.1

(Lyulcheva et al., 2008)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing pouch phenotype, non-suppressible by p53^259H.GUS, Scer\GAL4^Act88F.PD

(Moon et al., 2008)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by p53^259H.GUS, Scer\GAL4^GMR.PF

(Moon et al., 2008)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has eye disc posterior to the morphogenetic furrow phenotype, non-suppressible by p53^5A-1-4

(Moon et al., 2008)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, non-suppressible by dap^UAS.cdNa, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, non-suppressible by CycE^AR95, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, non-suppressible by stg⁰¹²³⁵, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, non-suppressible by Cdk1², Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, non-suppressible by Cdk2^unspecified, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, non-suppressible by Cdk4^unspecified, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

E2f1^UAS.cNa, Scer\GAL4^Act88F.PD has wing blade phenotype, non-suppressible by Hsap\CDKN1A^UAS.cHa, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

Suppressor of

Statement

Reference

E2f1^UAS.cNa/Scer\GAL4^Act5C.PI is a suppressor | partially of adult posterior midgut epithelium | somatic clone phenotype of Phb1²⁰

(Zhao et al., 2022)

E2f1^UAS.cNa, Scer\GAL4^esg.PU is a suppressor of adult posterior midgut epithelium phenotype of Phb1^HMS00702, Scer\GAL4^esg.PU

(Zhao et al., 2022)

E2f1^UAS.cNa/Scer\GAL4^Act5C.PI is a suppressor | partially of adult posterior midgut epithelium | somatic clone phenotype of Phb2^Δ

(Zhao et al., 2022)

E2f1^UAS.cNa, Scer\GAL4^esg.PU is a suppressor of adult posterior midgut epithelium phenotype of Phb2^GD8538, Scer\GAL4^esg.PU

(Zhao et al., 2022)

E2f1^UAS.cNa/Scer\GAL4^Act5C.PI is a suppressor of adult posterior midgut epithelium | somatic clone phenotype of dind^Δ9

(Zhao et al., 2022)

E2f1^UAS.cNa, Scer\GAL4^esg.PU is a suppressor of adult posterior midgut epithelium phenotype of Scer\GAL4^esg.PU, dind^{RNAi.UAS.RNAi}

(Zhao et al., 2022)

E2f1^UAS.cNa, Dp^UAS.cDa, Scer\GAL4^Tub.PU is a suppressor of follicle stem cell | somatic clone phenotype of CycE^WX

(Wang and Kalderon, 2009)

Scer\GAL4^Tub.PU, Scer\GAL4^Act5C.PI, E2f1^UAS.cNa/Dp^UAS.cDa is a suppressor of follicle stem cell | somatic clone phenotype of CycE^AR95/CycE^WX.UAS.cWa, Scer\GAL4^Act5C.PI, Scer\GAL4^Tub.PU

(Wang and Kalderon, 2009)

E2f1^UAS.cNa, Dp^UAS.cDa, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of arm^S44Y.GMR

(Morris et al., 2008)

E2f1^UAS.cNa, Dp^UAS.cDa, Scer\GAL4^vg.int2.1, BacA\p35^UAS.cHa is a suppressor of wing blade phenotype of vg^83b27

(Legent et al., 2006)

Scer\GAL4^ptc-559.1, E2f1^UAS.cNa, BacA\p35^UAS.cHa is a suppressor of wing phenotype of vg^null

(Delanoue et al., 2004)

NOT Suppressor of

Statement

Reference

E2f1^UAS.cNa, Dp^UAS.cDa, CycA^UAS.cWa, Scer\GAL4^GMR.PF is a non-suppressor of eye disc | somatic clone phenotype of Delta^RevF10

(Baonza and Freeman, 2005)

Other

Statement

Reference

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^esg.PU has male accessory gland secondary cell phenotype

(Sekar et al., 2023)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^NP1624 has somatic cell of testis phenotype

(Sainz de la Maza et al., 2022)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^en.PU has wing disc posterior compartment | third instar larval stage phenotype

(Zhang et al., 2021)

Dp^UAS.cDa, E2f1⁰⁷¹⁷², E2f1^UAS.cNa, Scer\GAL4^Tub.PU has wing disc | somatic clone | third instar larval stage phenotype

(Zhang et al., 2021)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.long has eye phenotype

(Bervoets et al., 2019)

Dp^UAS.cDa, E2f1^UAS.cNa, Hsap\YARS1^E196K.UAS, Scer\GAL4^GMR.long has eye phenotype

(Bervoets et al., 2019)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^Su(H).GBE has adult midgut phenotype

(Kohlmaier et al., 2015)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^{Delta-05151-G} has adult midgut phenotype

(Kohlmaier et al., 2015)

Cdk2^UAS.Tag:MYC, CycE^UAS.cLa, Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^{Delta-05151-G} has adult midgut phenotype

(Kohlmaier et al., 2015)

Cdk2^UAS.Tag:MYC, CycE^UAS.cLa, Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^Su(H).GBE has adult midgut phenotype

(Kohlmaier et al., 2015)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has eye disc phenotype

(Truscott et al., 2011, Baonza and Freeman, 2005)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^ptc-559.1 has wing disc phenotype

(Lyulcheva et al., 2008, Brennecke et al., 2003)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PF has eye disc posterior to the morphogenetic furrow phenotype

(Moon et al., 2008)

Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^{elav.Switch.PO} has adult brain phenotype

(Khurana et al., 2006)

BacA\p35^UAS.cHa, Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^vg.int2.1 has wing phenotype

(Legent et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

The co-expression of E2f1^UAS.cNa and Dp^UAS.cDa under the control of Scer\GAL4^en.PU induces increased mitosis in the third instar larval wing disc posterior compartment.

Third instar larval wing disc clones homozygous for E2f1⁰⁷¹⁷² and that also co-express E2f1^UAS.cNa and Dp^UAS.cDa under the control of Scer\GAL4^Tub.PU have more cells than controls.

(Zhang et al., 2021)

Co-expressing E2f1^UAS.cNa and Dp^UAS.cDa under the control of Scer\GAL4^GMR.long results in a rough eye phenotype.

(Bervoets et al., 2019)

Expression of mir-11^{Scer\UAS.T:Disc\RFP-DsRed2} suppresses the apoptosis seen in the wings of newly eclosed flies expressing E2f1^Scer\UAS.cNa under the control of Scer\GAL4^Act88F.PD.

Expression of mir-998^Scer\UAS.cTa does not suppress the apoptosis seen in the wings of newly eclosed flies expressing E2f1^Scer\UAS.cNa under the control of Scer\GAL4^Act88F.PD.

Expression of mir-11^{Scer\UAS.T:Disc\RFP-DsRed2} suppresses the apoptosis seen in the eye disc in flies expressing E2f1^Scer\UAS.cNa and Dp^Scer\UAS.cDa under the control of Scer\GAL4^GMR.PU.

Expression of mir-998^Scer\UAS.cTa does not suppress the apoptosis seen in the eye disc in flies expressing expressing E2f1^Scer\UAS.cNa and Dp^Scer\UAS.cDa under the control of Scer\GAL4^GMR.PU.

(Truscott et al., 2014)

Cells posterior to the second mitotic wave in the eye disc which are co-expressing E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa under the control of Scer\GAL4^GMR.PF undergo ectopic S phases. In addition, independently of the ectopic S phases, co-expression of E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa under the control of Scer\GAL4^GMR.PF results in the induction of apoptosis in the eye disc.

The addition of mir-11^{Scer\UAS.T:Disc\RFP-DsRed2} does not prevent the ectopic S phases which are induced posterior to the morphogenetic furrow by co-expression of E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa under the control of Scer\GAL4^GMR.PF. However, co-expression of mir-11^{Scer\UAS.T:Disc\RFP-DsRed2} does suppress the ability of co-expression of E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa under the control of Scer\GAL4^GMR.PF to induce apoptosis in the eye disc.

Co-expression of mir-11^{Scer\UAS.T:Disc\RFP-DsRed2} strongly suppresses the wing defects caused by expression of E2f^Scer\UAS.cNa under the control of Scer\GAL4^Act88F.PD.

(Truscott et al., 2011)

Scer\GAL4^tub-driven co-expression of E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa in follicle stem cell (FSC) clones suppresses the CycE^WX-associated defective FSC-maintenance phenotype.

Scer\GAL4^tub- and Scer\GAL4^Act5C.PI-driven co-expression of E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa in CycE^AR95 follicle stem cell (FSC) clones also expressing CycE^{WX.Scer\UAS.cWa} suppresses the CycE^AR95-associated defective FSC-maintenance phenotype.

(Wang and Kalderon, 2009)

Overexpression of E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa in a stripe of cells in the wing using Scer\GAL4^ptc-559.1 results in high levels of cell death.

Co-expression of pico^{Scer\UAS.T:Zzzz\His6,T:Hsap\MYC} with E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa in a stripe of cells in the wing using Scer\GAL4^ptc-559.1 fails to suppress cell death.

(Lyulcheva et al., 2008)

The wing phenotype of Scer\GAL4^Act88F.PD, E2f^Scer\UAS.cNa is suppressed by co-expression of Rbf^Scer\UAS.cDa.

The wing phenotype of Scer\GAL4^Act88F.PD, E2f^Scer\UAS.cNa is unaffected by co-expression of p53^259H.GUS.

The rough eye phenotype of Scer\GAL4^GMR.PF, E2f^Scer\UAS.cNa, Dp^Scer\UAS.cDa flies is unaffected by co-expression of p53^259H.GUS.

Scer\GAL4^GMR.PF drives the expression of E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa in the posterior region of the eye disc inducing a pattern of apoptosis.

The apoptosis in the eye disc induced by the co-expression of E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa under the control of Scer\GAL4^GMR.PF is unaffected by homozygous p53^5A-1-4.

(Moon et al., 2008)

Co-expression of arm^{S2.Scer\UAS.T:Hsap\MYC} strongly suppresses the gnarled wing phenotype caused by expression of E2f^Scer\UAS.cNa under the control of Scer\GAL4^Act88F.PD.

Co-expression of pan^Scer\UAS.cWa partially suppresses the gnarled wing phenotype caused by expression of E2f^Scer\UAS.cNa under the control of Scer\GAL4^Act88F.PD.

Co-expression of sgg^Scer\UAS.cBa enhances the gnarled wing phenotype caused by expression of E2f^Scer\UAS.cNa under the control of Scer\GAL4^Act88F.PD.

Simultaneous expression of E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa under the control of Scer\GAL4^GMR.PU partially suppresses the rough eye phenotype caused by arm^S44Y.GMR.

(Morris et al., 2008)

Expression of Dp^Scer\UAS.cDa and E2f^Scer\UAS.cNa in the brain under the control of Scer\GAL4^elav.PLu results in lethality.

10 day old brains from animals expressing Dp^Scer\UAS.cDa and E2f^Scer\UAS.cNa under the control of the selective driver Scer\GAL4^{elav.Switch.PO} display marked loss of cortical neurons and rarefaction of the underlying neuropil compared to controls.

(Khurana et al., 2006)

The blackened and rough eye phenotype resulting from the expression of Scer\GAL4^GMR.PF-driven E2f^Scer\UAS.cNa is enhanced by co-expression of Aac11^{dsRNA.Scer\UAS}.

(Morris et al., 2006)

Co-expression of E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa under the control of Scer\GAL4^GMR.PF produces significant excess mitoses in the eye disc.

Co-expression of Dl^Scer\UAS.cJa results in a moderate but reproducible and statistically significant increase in the number of mitoses seen in eye discs expressing E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa under the control of Scer\GAL4^GMR.PF.

Co-overexpression of CycA^Scer\UAS.cWa, E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa (using Scer\GAL4^GMR.PF) does not significantly rescue the S phase phenotype seen in Dl^RevF10 clones in a Minute/+ background.

(Baonza and Freeman, 2005)

When E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa are driven by Scer\GAL4^ptc-559.1 cells in the wing disc overproliferate. Many of these cells drop out of the epithelial layer and have pycnotic nuclei. The addition of ban^EP3622 enhances the overproliferation phenotype seen in E2f^Scer\UAS.cNa, Dp^Scer\UAS.cDa, Scer\GAL4^ptc-559.1 animals. Fewer cells show pyknotic nuclei, though many cells still drop out of the epithelial layer.

(Brennecke et al., 2003)

Marked clones in the eye disc which are homozygous for scrib¹ and are co-expressing Dp^Scer\UAS.cDa, E2f^Scer\UAS.cNa and BacA\p35^Scer\UAS.cHa under the control of Scer\GAL4^Act5C.PI do not show metastatic behaviour.

(Pagliarini and Xu, 2003)

Co-expression of both E2f1^Scer\UAS.cNa and Dp^Scer\UAS.cDa in starved larvae under the control of Scer\GAL4^Act5C.PP is sufficient to drive most endoreplicating cells into S phase, as assayed by BrdU incorporation.

(Britton and Edgar, 1998)

Co-expression of Dp^Scer\UAS.cDa enhances the effects of E2f^Scer\UAS.cNa expression.

(Neufeld et al., 1998)

Xenogenetic Interactions

Statement

Reference

Additional expression of Hsap\YARS1^E196K.UAS enhances the rough eye phenotype induced by the co-expression of E2f1^UAS.cNa and Dp^UAS.cDa under the control of Scer\GAL4^GMR.long, leading to a decrease in eye size.

(Bervoets et al., 2019)

Co-expression of BacA\p35^Scer\UAS.cUa suppresses the induction of apoptosis in the eye disc caused by co-expression of E2f^Scer\UAS.cNa and Dp^Scer\UAS.cDa under the control of Scer\GAL4^GMR.PF.

(Truscott et al., 2011)

Co-expression of E2f^Scer\UAS.cNa, Dp^Scer\UAS.cDa and BacA\p35^Scer\UAS.cHa under the control of Scer\GAL4^vg.int2.1 results in a wing nicking phenotype, which is partially suppressed by vg^null/+.

Co-expression of E2f^Scer\UAS.cNa, Dp^Scer\UAS.cDa and BacA\p35^Scer\UAS.cHa under the control of Scer\GAL4^vg.int2.1 rescues wing appendage growth in vg^83b27 flies; wing blade features such as bristles, wing veins and margin are often seen in the rescued appendages.

Co-expression of E2f^Scer\UAS.cNa, Dp^Scer\UAS.cDa and BacA\p35^Scer\UAS.cHa under the control of Scer\GAL4^vg.int2.1 does not wing blade growth in vg^null flies and only a slight increase in wing hinge growth is seen.

(Legent et al., 2006)

Expression of E2f^Scer\UAS.cNa and BacA\p35^Scer\UAS.cHa under the control of Scer\GAL4^ptc-559.1 in vg^null mutant discs results in an increase in the number of cells in S-phase.

(Delanoue et al., 2004)

Complementation and Rescue Data

Rescues

E2f1^UAS.cNa/Scer\GAL4^GMR.PU rescues E2f1^RNAi.UAS.cJa

(Ji et al., 2012)

Comments

Co-expression of E2f^Scer\UAS.cNa rescues the rough eye phenotype caused by expression of E2f^{dsRNA.Scer\UAS.cJa} under the control of Scer\GAL4^GMR.PU.

(Ji et al., 2012)

Images (0)

Mutant

Wild-type

Stocks (4)

Bloomington

4774

w¹¹¹⁸; P{UAS-E2f1.N}5A P{UAS-Dp.D}8C/CyO

4770

w¹¹¹⁸; P{UAS-E2f1.N}3B P{UAS-Dp.D}1-4b/TM6B, Tb¹

Kyoto

107866