FlyBase Allele Report: Scer\GAL4[C164]

General Information

Symbol

Scer\GAL4^C164

Species

S. cerevisiae

Name

FlyBase ID

FBal0102842

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}C164

Carried in Construct

Also Known As

c164-GAL4, C164, c164GAL4, Gal4-C164

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GawB}C164

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | female

sensory neuron

(Slawson et al., 2011)

motor neuron

(Torroja et al., 1999)

Additional Information

Statement

Reference

Drives expression in motor neurons. Additionally, drives expression in several regions of the adult brain, including in the antennal lobes, mushroom bodies, adult gnathal ganglion (SOG) and par intercerebralis, but not in the ellipsoid body.

(FlyBase Curators, 2017)

Scer\GAL4^C164 drives expression throughout the brain but not in the ellipsoid body. Expression is also detected in a subset of clock neurons, including LNd and DN2 neurons. Expression in these clock cells is variable regarding the identity and number of the cells labeled.

(Jepson et al., 2012)

In the adult brain, Scer\GAL4^C164 drives expression in many cells in the central nervous system including in the antennal lobes, mushroom bodies, subesophageal ganglion, and pars intercerebralis, but not in the ellipsoid body. Scer\GAL4^C164 also drives expression in adult female, but not male, peripheral sensory neurons.

(Slawson et al., 2011)

Adult expression is observed in the central body complex and in the posterior tip of the thoracic ganglion.

(Monastirioti, 2003)

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal body color | adult stage, with Shaw^{tr.UAS.Tag:FLAG}

(Hodge et al., 2005)

abnormal body size | pharate adult stage, with Shaw^{tr.UAS.Tag:FLAG}

(Hodge et al., 2005)

abnormal eclosion, with Shaw^{tr.UAS.Tag:FLAG}

(Hodge et al., 2005)

abnormal flight | conditional, with Hsap\HTT^128Q.FL.UAS

(Romero et al., 2008)

abnormal locomotor behavior, with CASK^β-null, CASK^UAS.cBa

(Slawson et al., 2011)

abnormal locomotor behavior | adult stage, with para^Shu.UAS

(Kaas et al., 2016)

abnormal locomotor behavior | adult stage, with Shal^{DN.UAS.Tag:HA}

(Ping et al., 2011)

abnormal locomotor behavior | conditional, with Hsap\HTT^128Q.FL.UAS

(Romero et al., 2008)

abnormal locomotor behavior | larval stage, with Shal^{DN.UAS.Tag:HA}

(Ping et al., 2011)

abnormal locomotor behavior | third instar larval stage, with cbc^HMC06558

(Schmidt et al., 2022)

abnormal locomotor behavior | third instar larval stage, with Hsap\HTT^Q93.ex1.UAS

(Steinert et al., 2012)

abnormal locomotor behavior | third instar larval stage, with Hsap\SNCA^TP.UAS.cKa

(Yin et al., 2014)

abnormal locomotor behavior | third instar larval stage, with Hsap\SNCA^UAS.cFa

(Breda et al., 2015)

abnormal locomotor behavior | third instar larval stage, with Hsap\SNCA^UAS.cKa

(Breda et al., 2015, Yin et al., 2014)

abnormal locomotor behavior | third instar larval stage, with Hsap\SNCA^UAS.cUa

(Yin et al., 2014)

abnormal locomotor behavior | third instar larval stage, with Rab11^{S25N.UASp.YFP}

(Breda et al., 2015)

abnormal neuroanatomy, with Grip^RNAi.UAS

(Ataman et al., 2006)

abnormal neuroanatomy, with Mdoa\Ace^UAS.cKa

(Kim et al., 2011)

abnormal neuroanatomy, with Vap33^UAS.cPa

(Pennetta et al., 2002)

abnormal neurophysiology | third instar larval stage, with cpx^GD10482

(Cho et al., 2015)

chemical sensitive, with Shaw^{tr.UAS.Tag:FLAG}

(Hodge et al., 2005)

flightless, with Arl8^UAS.GFP, Arl8^e00336

(Rosa-Ferreira et al., 2018)

lethal, with Zzzz\CCG^90.UAS.EGFP

(Sofola et al., 2007)

lethal - all die before end of P-stage, with Shaw^{RA.UAS.Tag:FLAG}

(Hodge et al., 2005)

lethal - all die during embryonic stage, with cbc^HMC06558

(Schmidt et al., 2022)

majority die during P-stage, with cbc^HMC06558

(Schmidt et al., 2022)

partially lethal | male, with Shaw^{tr.UAS.Tag:FLAG}

(Hodge et al., 2005)

short lived, with Hsap\HTT^128Q.FL.UAS

(Romero et al., 2008)

short lived | chemical conditional, with Mdoa\Ace^UAS.cKa

(Kim et al., 2011)

some die during larval stage, with cbc^HMC06558

(Schmidt et al., 2022)

some die during pharate adult stage, with Shaw^{RA.UAS.Tag:FLAG}

(Hodge et al., 2005)

uncoordinated, with Shaw^{tr.UAS.Tag:FLAG}

(Hodge et al., 2005)

visible | adult stage A1, with Shaw^{tr.UAS.Tag:FLAG}

(Hodge et al., 2005)

Phenotype Manifest In

adult cuticle, with Shaw^{tr.UAS.Tag:FLAG}

(Hodge et al., 2005)

adult neuromuscular junction | conditional, with Hsap\HTT^128Q.FL.UAS

(Romero et al., 2008)

bouton, with Grip^RNAi.UAS

(Ataman et al., 2006)

bouton, with Vap33^UAS.cPa

(Pennetta et al., 2002)

bouton & microtubule, with Vap33^UAS.cPa

(Pennetta et al., 2002)

bouton | increased number, with wg^{UAS.cHa.Tag:HA}

(Packard et al., 2002)

indirect flight muscle motor neuron | conditional, with Hsap\HTT^128Q.FL.UAS

(Romero et al., 2008)

neuromuscular junction | third instar larval stage, with cpx^GD10482

(Cho et al., 2015)

NMJ bouton, with Appl^sd.UAS

(Ashley et al., 2005)

NMJ bouton | third instar larval stage, with cpx^GD10482

(Cho et al., 2015)

presynaptic active zone, with Grip^RNAi.UAS

(Ataman et al., 2006)

synapse, with Mdoa\Ace^UAS.cKa

(Kim et al., 2011)

synapse, with Vap33^UAS.cPa

(Pennetta et al., 2002)

thorax | adult stage, with para^Shu.UAS

(Kaas et al., 2016)

wing, with para^Shu.UAS

(Kaas et al., 2016)

wing, with Shaw^{tr.UAS.Tag:FLAG}

(Hodge et al., 2005)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^C164, Shaw^{tr.UAS.Tag:FLAG} has visible | adult stage A1 phenotype, enhanceable by Sh¹⁴

(Hodge et al., 2005)

Scer\GAL4^C164, Shaw^{tr.UAS.Tag:FLAG} has abnormal body size | pharate adult stage phenotype, enhanceable by Sh¹⁴

(Hodge et al., 2005)

Scer\GAL4^C164, Shaw^{tr.UAS.Tag:FLAG} has abnormal eclosion phenotype, enhanceable by Sh¹⁴

(Hodge et al., 2005)

Scer\GAL4^C164, Shaw^{RA.UAS.Tag:FLAG} has lethal | embryonic stage phenotype, enhanceable by Sh¹⁴

(Hodge et al., 2005)

Suppressed by

Statement

Reference

Hsap\SNCA^UAS.cFa, Scer\GAL4^C164 has abnormal locomotor behavior | third instar larval stage phenotype, suppressible by Rab11^UAS.EGFP, Scer\GAL4^C164

(Breda et al., 2015)

Hsap\SNCA^UAS.cKa, Scer\GAL4^C164 has abnormal locomotor behavior | third instar larval stage phenotype, suppressible by Rab11^UAS.EGFP, Scer\GAL4^C164

(Breda et al., 2015)

Hsap\SNCA^UAS.cUa, Scer\GAL4^C164 has abnormal locomotor behavior | third instar larval stage phenotype, suppressible by Rab8^UASp.YFP, Scer\GAL4^C164

(Yin et al., 2014)

Hsap\SNCA^TP.UAS.cKa, Scer\GAL4^C164 has abnormal locomotor behavior | third instar larval stage phenotype, suppressible by Rab8^UASp.YFP, Scer\GAL4^C164

(Yin et al., 2014)

Hsap\SNCA^UAS.cKa, Scer\GAL4^C164 has abnormal locomotor behavior | third instar larval stage phenotype, suppressible by Rab8^UASp.YFP, Scer\GAL4^C164

(Yin et al., 2014)

Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^C164 has abnormal locomotor behavior | third instar larval stage phenotype, suppressible by Scer\GAL4^elav-C155/Rab11^UAS.EGFP

(Steinert et al., 2012)

Hsap\HTT^128Q.FL.UAS, Scer\GAL4^C164 has abnormal locomotor behavior | conditional phenotype, suppressible by Syx1A^Δ229/Syx1A[+]

(Romero et al., 2008)

NOT suppressed by

Statement

Reference

Hsap\SNCA^UAS.cKa, Scer\GAL4^C164 has abnormal locomotor behavior | third instar larval stage phenotype, non-suppressible by Rab11^{S25N.UASp.YFP}, Scer\GAL4^C164

(Breda et al., 2015)

Suppressor of

Statement

Reference

Rab11^UAS.EGFP, Scer\GAL4^C164 is a suppressor of abnormal locomotor behavior | third instar larval stage phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^C164

(Breda et al., 2015)

Rab11^UAS.EGFP, Scer\GAL4^C164 is a suppressor of abnormal locomotor behavior | third instar larval stage phenotype of Hsap\SNCA^UAS.cKa, Scer\GAL4^C164

(Breda et al., 2015)

Hsap\OSBPL8^UAS.Tag:HA/Scer\GAL4^C164 is a suppressor of abnormal flight | progressive phenotype of Vap33^Δ31, Vap33^ALS8

(Moustaqim-Barrette et al., 2014)

Hsap\OSBPL8^UAS.Tag:HA/Scer\GAL4^C164 is a suppressor | partially of short lived phenotype of Vap33^Δ31, Vap33^ALS8

(Moustaqim-Barrette et al., 2014)

Rab8^UASp.YFP, Scer\GAL4^C164 is a suppressor of abnormal locomotor behavior | third instar larval stage phenotype of Hsap\SNCA^UAS.cUa, Scer\GAL4^C164

(Yin et al., 2014)

Rab8^UASp.YFP, Scer\GAL4^C164 is a suppressor of abnormal locomotor behavior | third instar larval stage phenotype of Hsap\SNCA^TP.UAS.cKa, Scer\GAL4^C164

(Yin et al., 2014)

Rab8^UASp.YFP, Scer\GAL4^C164 is a suppressor of abnormal locomotor behavior | third instar larval stage phenotype of Hsap\SNCA^UAS.cKa, Scer\GAL4^C164

(Yin et al., 2014)

Scer\GAL4^C164/Mdoa\Ace^UAS.cKa is a suppressor of abnormal neuroanatomy phenotype of Ace^PL00568

(Kim et al., 2011)

dnc^UAS.cCa/Scer\GAL4^C164 is a suppressor of abnormal neuroanatomy phenotype of slo¹

(Lee and Wu, 2010)

Hsap\VAPB^P56S.UAS/Scer\GAL4^C164 is a suppressor of lethal phenotype of Vap33^Δ20

(Chai et al., 2008)

Hsap\VAPB^UAS.cCa/Scer\GAL4^C164 is a suppressor of lethal | larval stage phenotype of Vap33^Δ448

(Chai et al., 2008)

Hsap\VAPB^UAS.cCa/Scer\GAL4^C164 is a suppressor of abnormal neurophysiology phenotype of Vap33^Δ448

(Chai et al., 2008)

Hsap\VAPB^P56S.UAS/Scer\GAL4^C164 is a suppressor of lethal phenotype of Vap33^Δ448

(Chai et al., 2008)

NOT Suppressor of

Statement

Reference

Rab11^{S25N.UASp.YFP}, Scer\GAL4^C164 is a non-suppressor of abnormal locomotor behavior | third instar larval stage phenotype of Hsap\SNCA^UAS.cKa, Scer\GAL4^C164

(Breda et al., 2015)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^C164, Shaw^{tr.UAS.Tag:FLAG} has wing phenotype, enhanceable by Sh¹⁴

(Hodge et al., 2005)

Scer\GAL4^C164, Shaw^{tr.UAS.Tag:FLAG} has adult cuticle phenotype, enhanceable by Sh¹⁴

(Hodge et al., 2005)

Suppressed by

Statement

Reference

Appl^sd.UAS, Scer\GAL4^C164 has NMJ bouton phenotype, suppressible by Fas2[+]/Fas2^e76, Scer\GAL4^C164

(Ashley et al., 2005)

Suppressor of

Statement

Reference

Scer\GAL4^C164/Mdoa\Ace^UAS.cKa is a suppressor of NMJ bouton phenotype of Ace^PL00568

(Kim et al., 2011)

dnc^UAS.cCa/Scer\GAL4^C164 is a suppressor of NMJ bouton | increased number phenotype of slo¹

(Lee and Wu, 2010)

dnc^UAS.cCa/Scer\GAL4^C164 is a suppressor of neuromuscular junction phenotype of slo¹

(Lee and Wu, 2010)

Hsap\VAPB^UAS.cCa/Scer\GAL4^C164 is a suppressor of NMJ bouton phenotype of Vap33^Δ448

(Chai et al., 2008)

Hsap\VAPB^UAS.cCa/Scer\GAL4^C164 is a suppressor of synapse phenotype of Vap33^Δ448

(Chai et al., 2008)

Fas2^UAS.cAa/Scer\GAL4^C164 is a suppressor of NMJ bouton phenotype of Appl^d

(Ashley et al., 2005)

Fas2[+]/Fas2^e76, Scer\GAL4^C164 is a suppressor of NMJ bouton phenotype of Appl^sd.UAS, Scer\GAL4^C164

(Ashley et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^C164/Arl8^UAS.GFP rescues Arl8^e00336

(Rosa-Ferreira et al., 2018)

Trpml^UAS.cVa/Scer\GAL4^C164 rescues Trpml¹

(Wong et al., 2015)

Vap33^UAS.cPa/Scer\GAL4^C164 rescues Vap33^unspecified

(Han et al., 2012)

dysc^UAS.long/Scer\GAL4^C164 rescues dysc^s168/dysc^c03838

(Jepson et al., 2012)

loj^UAS.N9d/Scer\GAL4^C164 rescues loj⁰⁰⁸⁹⁸/loj⁰⁴⁰²⁶

(Saleem et al., 2012)

CASK^UAS.cBa/Scer\GAL4^C164 rescues CASK^β-null

(Slawson et al., 2011)

Tbh^UAS.cMa/Scer\GAL4^C164 rescues Tbh^nM18

(Monastirioti, 2003)

Vap33^UAS.cPa/Scer\GAL4^C164 rescues Vap33^Δ20

(Pennetta et al., 2002)

Vap33^UAS.cPa/Scer\GAL4^C164 rescues Vap33^Δ448

(Pennetta et al., 2002)

Fails to rescue

eca^UASp.cSa/Scer\GAL4^C164 fails to rescue Df(3R)GB104/eca¹

(Saleem et al., 2012)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

33807

P{GawB}C164

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^C164

Name Synonyms

Secondary FlyBase IDs

References (40)

Report Sections

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